DOCK9 (dedicator of cytokinesis 9)

2014-11-01  

Identity

HGNC
LOCATION
13q32.3
LOCUSID
ALIAS
ZIZ1,ZIZIMIN1
FUSION GENES

Other Information

Locus ID:

NCBI: 23348
MIM: 607325
HGNC: 14132
Ensembl: ENSG00000088387

Variants:

dbSNP: 23348
ClinVar: 23348
TCGA: ENSG00000088387
COSMIC: DOCK9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000088387ENST00000339416Q6ZSL5
ENSG00000088387ENST00000340449Q5JUD8
ENSG00000088387ENST00000376460Q9BZ29
ENSG00000088387ENST00000400228H0Y3S1
ENSG00000088387ENST00000419908H7BZ79
ENSG00000088387ENST00000427887A0A0A0MT38
ENSG00000088387ENST00000442173A0A0A0MSY4
ENSG00000088387ENST00000448493A0A088AWN3
ENSG00000088387ENST00000449796X6RGR3
ENSG00000088387ENST00000450257H0Y572
ENSG00000088387ENST00000451563Q5JUD3
ENSG00000088387ENST00000479769A0A0D9SF41
ENSG00000088387ENST00000627024Q9BZ29
ENSG00000088387ENST00000630992A0A0D9SFH5
ENSG00000088387ENST00000638020A0A1B0GVL8
ENSG00000088387ENST00000652315Q9BZ29

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Factors involved in megakaryocyte development and platelet productionREACTOMER-HSA-983231

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
121725522002Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins.51
197451542009Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor.46
180562642008Specific recognition of Rac2 and Cdc42 by DOCK2 and DOCK9 guanine nucleotide exchange factors.15
187290742008Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1.15
179354862008Function of the N-terminus of zizimin1: autoinhibition and membrane targeting.13
177286662007Sequence variation in DOCK9 and heterogeneity in bipolar disorder.12
177286662007Sequence variation in DOCK9 and heterogeneity in bipolar disorder.12
266415462015Variant c.2262A>C in DOCK9 Leads to Exon Skipping in Keratoconus Family.6
198090892009Snapshots form a big picture of guanine nucleotide exchange.2

Citation

Dessen P

DOCK9 (dedicator of cytokinesis 9)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62592/dock9-(dedicator-of-cytokinesis-9)