DONSON (DNA replication fork stabilization factor DONSON)

2014-11-01  

Identity

HGNC
DONSON
LOCATION
21q22.11
LOCUSID
29980
ALIAS
B17,C21orf60,MIMIS,MISSLA
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 29980
MIM: 611428
HGNC: 2993
Ensembl: ENSG00000159147

Variants:

dbSNP: 29980
ClinVar: 29980
TCGA: ENSG00000159147
COSMIC: DONSON

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000159147ENST00000303071Q9NYP3
ENSG00000159147ENST00000303113F8W8A5
ENSG00000159147ENST00000417871F8WC22
ENSG00000159147ENST00000432378C9J4K5
ENSG00000159147ENST00000437395H7C1C1
ENSG00000159147ENST00000439593V9GY84
ENSG00000159147ENST00000440810H7C1M7
ENSG00000159147ENST00000442660H7C304
ENSG00000159147ENST00000444517H7C006
ENSG00000159147ENST00000453626C9JSP0
ENSG00000159147ENST00000457359F8WD19

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
286301772017Integrated genome and transcriptome sequencing identifies a noncoding mutation in the genome replication factor DONSON as the cause of microcephaly-micromelia syndrome.13
319755702020Replisome genes regulation by antitumor miR-101-5p in clear cell renal cell carcinoma.1

Citation

Dessen P

DONSON (DNA replication fork stabilization factor DONSON)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62598/donson-(dna-replication-fork-stabilization-factor-donson)