Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10589
MIM: 602289
HGNC: 3019
Ensembl: ENSG00000175550
Variants:
dbSNP: 10589
ClinVar: 10589
TCGA: ENSG00000175550
COSMIC: DRAP1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by Activin | REACTOME | R-HSA-1502540 |
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Signaling by NODAL | REACTOME | R-HSA-1181150 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 19204005 | 2009 | Regulation of nuclear import and export of negative cofactor 2. | 7 |
| 19204005 | 2009 | Regulation of nuclear import and export of negative cofactor 2. | 7 |
| 17548813 | 2007 | Global distribution of negative cofactor 2 subunit-alpha on human promoters. | 18 |
| 17994103 | 2007 | NC2 mobilizes TBP on core promoter TATA boxes. | 39 |
| 17548813 | 2007 | Global distribution of negative cofactor 2 subunit-alpha on human promoters. | 18 |
| 17994103 | 2007 | NC2 mobilizes TBP on core promoter TATA boxes. | 39 |
| 15509807 | 2004 | NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein. | 15 |
| 15509807 | 2004 | NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein. | 15 |
| 12477712 | 2003 | Hypoxia actively represses transcription by inducing negative cofactor 2 (Dr1/DrAP1) and blocking preinitiation complex assembly. | 16 |
| 12477712 | 2003 | Hypoxia actively represses transcription by inducing negative cofactor 2 (Dr1/DrAP1) and blocking preinitiation complex assembly. | 16 |
Citation
Dessen P
DRAP1 (DR1 associated protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62636/submit-meetings/gene-explorer/
