Identity
HGNC
LOCATION
18q12.1
LOCUSID
ALIAS
D18S892E,DRP3,DTN,DTN-A,LVNC1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1837
MIM: 601239
HGNC: 3057
Ensembl: ENSG00000134769
Variants:
dbSNP: 1837
ClinVar: 1837
TCGA: ENSG00000134769
COSMIC: DTNA
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447199 | Bipolar Disorder | Disease | Literature, MultilinkAnnotation | associated | 24718920 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36799992 | 2023 | Variants in DTNA cause a mild, dominantly inherited muscular dystrophy. | 0 |
| 36799992 | 2023 | Variants in DTNA cause a mild, dominantly inherited muscular dystrophy. | 0 |
| 35148685 | 2022 | Whole-exome sequencing reveals a rare missense variant in DTNA in an Iranian pedigree with early-onset atrial fibrillation. | 6 |
| 35148685 | 2022 | Whole-exome sequencing reveals a rare missense variant in DTNA in an Iranian pedigree with early-onset atrial fibrillation. | 6 |
| 32737801 | 2021 | Oncogenic microRNA-301b regulates tumor repressor dystrobrevin alpha to facilitate cell growth, invasion and migration in esophageal cancer. | 5 |
| 32737801 | 2021 | Oncogenic microRNA-301b regulates tumor repressor dystrobrevin alpha to facilitate cell growth, invasion and migration in esophageal cancer. | 5 |
| 32619495 | 2020 | DTNA promotes HBV-induced hepatocellular carcinoma progression by activating STAT3 and regulating TGFβ1 and P53 signaling. | 6 |
| 32619495 | 2020 | DTNA promotes HBV-induced hepatocellular carcinoma progression by activating STAT3 and regulating TGFβ1 and P53 signaling. | 6 |
| 29508483 | 2018 | Barth syndrome associated with triple mutation. | 0 |
| 29508483 | 2018 | Barth syndrome associated with triple mutation. | 0 |
| 25305078 | 2015 | Identification of two novel mutations in FAM136A and DTNA genes in autosomal-dominant familial Meniere's disease. | 47 |
| 25959029 | 2015 | Localization of α-Dystrobrevin in Cajal Bodies and Nucleoli: A New Role for α-Dystrobrevin in the Structure/Stability of the Nucleolus. | 2 |
| 25305078 | 2015 | Identification of two novel mutations in FAM136A and DTNA genes in autosomal-dominant familial Meniere's disease. | 47 |
| 25959029 | 2015 | Localization of α-Dystrobrevin in Cajal Bodies and Nucleoli: A New Role for α-Dystrobrevin in the Structure/Stability of the Nucleolus. | 2 |
| 24014171 | 2013 | Ordered disorder of the astrocytic dystrophin-associated protein complex in the norm and pathology. | 7 |
Citation
Dessen P
DTNA (dystrobrevin alpha)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62664/dtna-(dystrobrevin-alpha)
