Department of Biological Sciences, Middle East Technical University, Ankara, TURKEY, gozdek@metu.edu.tr; didem.doken@metu.edu.tr; erson@metu.edu.tr
Eukaryotic Translation Initiation Factor 2B Subunit Gamma (EIF2B3) gene maps to 1p34.1, consists of 12 exons and 11 introns (NCBI Reference Sequence: NC_000001.11: 44850522-44986722). The locus generates three transcripts as a result of alternative splicing. EIF2B3 protein is composed of 452 amino acids and it is one of the important subunits of EIF2B decameric complex with guanine nucleotide exchange factor (GEF) activity. EIF2B3 protein plays a crucial role in the rate-limiting step of translation initiation.
Gözde Köksal-Biçakci ; Didem Naz Dioken ; Ayse Elif Erson-Bensan
EIF2B3 (Eukaryotic Translation Initiation Factor 2B Subunit Gamma)
Atlas Genet Cytogenet Oncol Haematol. 2021-01-01
Online version: http://atlasgeneticsoncology.org/gene/62775/js/web-card-gene.js