Identity
HGNC
LOCATION
3q27.1
LOCUSID
ALIAS
CACH,CLE,EIF-2B,EIF2Bepsilon,LVWM
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8893
MIM: 603945
HGNC: 3261
Ensembl: ENSG00000145191
Variants:
dbSNP: 8893
ClinVar: 8893
TCGA: ENSG00000145191
COSMIC: EIF2B5
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37674283 | 2023 | A novel missense variant in EIF2B5 identified in a consanguineous Iranian family with vanishing white matter disease and a brief review of the literature. | 0 |
| 37674283 | 2023 | A novel missense variant in EIF2B5 identified in a consanguineous Iranian family with vanishing white matter disease and a brief review of the literature. | 0 |
| 35710311 | 2022 | CircAHNAK upregulates EIF2B5 expression to inhibit the progression of ovarian cancer by modulating the JAK2/STAT3 signaling pathway. | 4 |
| 35710311 | 2022 | CircAHNAK upregulates EIF2B5 expression to inhibit the progression of ovarian cancer by modulating the JAK2/STAT3 signaling pathway. | 4 |
| 32000373 | 2020 | Low EIF2B5 expression predicts poor prognosis in ovarian cancer. | 2 |
| 32293553 | 2020 | Foetal onset of EIF2B related disorder in two siblings: cerebellar hypoplasia with absent Bergmann glia and severe hypomyelination. | 3 |
| 32665273 | 2020 | eIF2B as a Target for Viral Evasion of PKR-Mediated Translation Inhibition. | 16 |
| 33300869 | 2020 | Vanishing white matter disease expression of truncated EIF2B5 activates induced stress response. | 11 |
| 32000373 | 2020 | Low EIF2B5 expression predicts poor prognosis in ovarian cancer. | 2 |
| 32293553 | 2020 | Foetal onset of EIF2B related disorder in two siblings: cerebellar hypoplasia with absent Bergmann glia and severe hypomyelination. | 3 |
| 32665273 | 2020 | eIF2B as a Target for Viral Evasion of PKR-Mediated Translation Inhibition. | 16 |
| 33300869 | 2020 | Vanishing white matter disease expression of truncated EIF2B5 activates induced stress response. | 11 |
| 28961236 | 2017 | Transcriptome analysis of hypoxic cancer cells uncovers intron retention in EIF2B5 as a mechanism to inhibit translation. | 34 |
| 28961236 | 2017 | Transcriptome analysis of hypoxic cancer cells uncovers intron retention in EIF2B5 as a mechanism to inhibit translation. | 34 |
| 25457085 | 2015 | A Japanese girl with an early-infantile onset vanishing white matter disease resembling Cree leukoencephalopathy. | 2 |
Citation
Dessen P
EIF2B5 (eukaryotic translation initiation factor 2B subunit epsilon)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62776/eif2b5-(eukaryotic-translation-initiation-factor-2b-subunit-epsilon)
