EIF4E1B (eukaryotic translation initiation factor 4E family member 1B)

2014-11-01  

Identity

HGNC
EIF4E1B
LOCATION
5q35.2
LOCUSID
253314
ALIAS
-

Other Information

Locus ID:

NCBI: 253314
HGNC: 33179
Ensembl: ENSG00000175766

Variants:

dbSNP: 253314
ClinVar: 253314
TCGA: ENSG00000175766
COSMIC: EIF4E1B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000175766ENST00000318682A6NMX2
ENSG00000175766ENST00000504597A6NMX2
ENSG00000175766ENST00000505497H0Y8X3
ENSG00000175766ENST00000510660D6RHE2
ENSG00000175766ENST00000647833A6NMX2

Expression (GTEx)

0
1
2
3
4
5
6
7
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
mTOR signaling pathwayKEGGko04150
Insulin signaling pathwayKEGGko04910
mTOR signaling pathwayKEGGhsa04150
Insulin signaling pathwayKEGGhsa04910
RNA transportKEGGko03013
RNA transportKEGGhsa03013
eIF4F complexKEGGhsa_M00428
PI3K-Akt signaling pathwayKEGGhsa04151
PI3K-Akt signaling pathwayKEGGko04151
HIF-1 signaling pathwayKEGGhsa04066
eIF4F complexKEGGM00428
Longevity regulating pathwayKEGGhsa04211
EGFR tyrosine kinase inhibitor resistanceKEGGko01521
EGFR tyrosine kinase inhibitor resistanceKEGGhsa01521

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381779022024eIF4E1b is a non-canonical eIF4E protecting maternal dormant mRNAs.2
381779022024eIF4E1b is a non-canonical eIF4E protecting maternal dormant mRNAs.2

Citation

Dessen P

EIF4E1B (eukaryotic translation initiation factor 4E family member 1B)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62784/eif4e1b-(eukaryotic-translation-initiation-factor-4e-family-member-1b)