Identity
HGNC
LOCATION
10q24.31
LOCUSID
ALIAS
C10orf69,Erlin-1,KE04,KEO4,SPFH1,SPG62
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10613
MIM: 611604
HGNC: 16947
Ensembl: ENSG00000107566
Variants:
dbSNP: 10613
ClinVar: 10613
TCGA: ENSG00000107566
COSMIC: ERLIN1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000107566 | ENST00000370408 | B0QZ43 |
| ENSG00000107566 | ENST00000407654 | O75477 |
| ENSG00000107566 | ENST00000421367 | O75477 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37683630 | 2023 | Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection. | 2 |
| 37683630 | 2023 | Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection. | 2 |
| 32776921 | 2020 | Disruption of the ERLIN-TM6SF2-APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease. | 21 |
| 32776921 | 2020 | Disruption of the ERLIN-TM6SF2-APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease. | 21 |
| 31810281 | 2019 | The Host Factor Erlin-1 is Required for Efficient Hepatitis C Virus Infection. | 6 |
| 31810281 | 2019 | The Host Factor Erlin-1 is Required for Efficient Hepatitis C Virus Infection. | 6 |
| 23477746 | 2013 | The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. | 29 |
| 24217618 | 2013 | Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis. | 39 |
| 24217618 | 2013 | Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis. | 39 |
| 23477746 | 2013 | The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. | 29 |
| 24217618 | 2013 | Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis. | 39 |
| 24217618 | 2013 | Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis. | 39 |
| 21048031 | 2011 | Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph. | 5 |
| 21048031 | 2011 | Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph. | 5 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
Citation
Dessen P
ERLIN1 (ER lipid raft associated 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62895/erlin1-(er-lipid-raft-associated-1)
