ETFDH (electron transfer flavoprotein dehydrogenase)

2014-11-01  

Identity

HGNC
LOCATION
4q32.1
LOCUSID
ALIAS
ETFQO,MADD
FUSION GENES

Other Information

Locus ID:

NCBI: 2110
MIM: 231675
HGNC: 3483
Ensembl: ENSG00000171503

Variants:

dbSNP: 2110
ClinVar: 2110
TCGA: ENSG00000171503
COSMIC: ETFDH

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171503ENST00000307738Q16134
ENSG00000171503ENST00000507475D6RAD5
ENSG00000171503ENST00000511912Q16134
ENSG00000171503ENST00000512251D6RJF8

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transportREACTOMER-HSA-1428517
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.REACTOMER-HSA-163200
Respiratory electron transportREACTOMER-HSA-611105

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA447197Attention Deficit Disorder with HyperactivityDiseaseClinicalAnnotationassociatedPD29382897
PA450464methylphenidateChemicalClinicalAnnotationassociatedPD29382897

References

Pubmed IDYearTitleCitations
338237242021ETF dehydrogenase advances in molecular genetics and impact on treatment.15
347044212021Screening of multiple acyl-CoA dehydrogenase deficiency in newborns and follow-up of patients.5
347826062021Multiple acyl-CoA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection.10
338237242021ETF dehydrogenase advances in molecular genetics and impact on treatment.15
347044212021Screening of multiple acyl-CoA dehydrogenase deficiency in newborns and follow-up of patients.5
347826062021Multiple acyl-CoA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection.10
323931892020A novel electron transfer flavoprotein dehydrogenase (ETFDH) gene mutation identified in a newborn with glutaric acidemia type II: a case report of a Chinese family.7
328044292020Mitochondrial energetic impairment in a patient with late-onset glutaric acidemia Type 2.4
330002342020Clinical characteristics and gene mutation analysis of an adult patient with ETFDH‑related multiple acyl‑CoA dehydrogenase deficiency.1
323931892020A novel electron transfer flavoprotein dehydrogenase (ETFDH) gene mutation identified in a newborn with glutaric acidemia type II: a case report of a Chinese family.7
328044292020Mitochondrial energetic impairment in a patient with late-onset glutaric acidemia Type 2.4
330002342020Clinical characteristics and gene mutation analysis of an adult patient with ETFDH‑related multiple acyl‑CoA dehydrogenase deficiency.1
314183422019Molecular and Clinical Investigations on Portuguese Patients with Multiple acyl-CoA Dehydrogenase Deficiency.5
315989462019[Analysis of ETFDH gene variation in a Chinese family affected with lipid storage myopathy].0
317041522019Expression and significance of ETFDH in hepatocellular carcinoma.9

Citation

Dessen P

ETFDH (electron transfer flavoprotein dehydrogenase)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62928/etfdh-(electron-transfer-flavoprotein-dehydrogenase)