Identity
HGNC
LOCATION
1p36.22
LOCUSID
ALIAS
PM-Scl,PM/Scl-100,PMSCL,PMSCL2,RRP6,Rrp6p,p2,p3,p4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5394
MIM: 605960
HGNC: 9138
Ensembl: ENSG00000171824
Variants:
dbSNP: 5394
ClinVar: 5394
TCGA: ENSG00000171824
COSMIC: EXOSC10
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000171824 | ENST00000304457 | Q01780 |
| ENSG00000171824 | ENST00000376936 | Q01780 |
| ENSG00000171824 | ENST00000460196 | K7EJ37 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38279024 | 2024 | Hypoxia-driven deSUMOylation of EXOSC10 promotes adaptive changes in the transcriptome profile. | 2 |
| 38279024 | 2024 | Hypoxia-driven deSUMOylation of EXOSC10 promotes adaptive changes in the transcriptome profile. | 2 |
| 36912080 | 2023 | The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing. | 4 |
| 37701829 | 2023 | EXOSC10 is a novel hepatocellular carcinoma prognostic biomarker: a comprehensive bioinformatics analysis and experiment verification. | 0 |
| 36912080 | 2023 | The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing. | 4 |
| 37701829 | 2023 | EXOSC10 is a novel hepatocellular carcinoma prognostic biomarker: a comprehensive bioinformatics analysis and experiment verification. | 0 |
| 35902094 | 2022 | MPP6 stimulates both RRP6 and DIS3 to degrade a specified subset of MTR4-sensitive substrates in the human nucleus. | 2 |
| 35902094 | 2022 | MPP6 stimulates both RRP6 and DIS3 to degrade a specified subset of MTR4-sensitive substrates in the human nucleus. | 2 |
| 33580257 | 2021 | The clinical phenotype of systemic sclerosis patients with anti-PM/Scl antibodies: results from the EUSTAR cohort. | 16 |
| 34059908 | 2021 | RNA-regulatory exosome complex confers cellular survival to promote erythropoiesis. | 6 |
| 33580257 | 2021 | The clinical phenotype of systemic sclerosis patients with anti-PM/Scl antibodies: results from the EUSTAR cohort. | 16 |
| 34059908 | 2021 | RNA-regulatory exosome complex confers cellular survival to promote erythropoiesis. | 6 |
| 32350160 | 2020 | Exploration of Salmonella effector mutant strains on MTR4 and RRP6 degradation. | 3 |
| 32350160 | 2020 | Exploration of Salmonella effector mutant strains on MTR4 and RRP6 degradation. | 3 |
| 30840897 | 2019 | Rapid Depletion of DIS3, EXOSC10, or XRN2 Reveals the Immediate Impact of Exoribonucleolysis on Nuclear RNA Metabolism and Transcriptional Control. | 33 |
Citation
Dessen P
EXOSC10 (exosome component 10)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62949/exosc10
