Identity
HGNC
LOCATION
5q35.2
LOCUSID
ALIAS
ETEA,UBXD8,UBXN3B
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23197
MIM: 616935
HGNC: 24666
Ensembl: ENSG00000113194
Variants:
dbSNP: 23197
ClinVar: 23197
TCGA: ENSG00000113194
COSMIC: FAF2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000113194 | ENST00000261942 | Q96CS3 |
| ENSG00000113194 | ENST00000510730 | D6RBG6 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36799187 | 2023 | Role of ubiquitin regulatory X domain‑containing protein 3B in the development of hepatocellular carcinoma (Review). | 0 |
| 36799187 | 2023 | Role of ubiquitin regulatory X domain‑containing protein 3B in the development of hepatocellular carcinoma (Review). | 0 |
| 36377866 | 2022 | UBXN3B Controls Immunopathogenesis of Arthritogenic Alphaviruses by Maintaining Hematopoietic Homeostasis. | 2 |
| 36377866 | 2022 | UBXN3B Controls Immunopathogenesis of Arthritogenic Alphaviruses by Maintaining Hematopoietic Homeostasis. | 2 |
| 34739333 | 2021 | Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner. | 97 |
| 34739333 | 2021 | Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner. | 97 |
| 29899553 | 2018 | UBXN3B positively regulates STING-mediated antiviral immune responses. | 38 |
| 29899553 | 2018 | UBXN3B positively regulates STING-mediated antiviral immune responses. | 38 |
| 28882874 | 2017 | Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis. | 15 |
| 28882874 | 2017 | Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis. | 15 |
| 27295553 | 2016 | Peroxin-dependent targeting of a lipid-droplet-destined membrane protein to ER subdomains. | 51 |
| 27295553 | 2016 | Peroxin-dependent targeting of a lipid-droplet-destined membrane protein to ER subdomains. | 51 |
| 24378746 | 2014 | Cellular responses to excess fatty acids: focus on ubiquitin regulatory X domain-containing protein 8. | 4 |
| 24378746 | 2014 | Cellular responses to excess fatty acids: focus on ubiquitin regulatory X domain-containing protein 8. | 4 |
| 23297223 | 2013 | Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover. | 112 |
Citation
Dessen P
FAF2 (Fas associated factor family member 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62974/faf2-(fas-associated-factor-family-member-2)
