Identity
HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
C16orf36,YISKL
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 81889
MIM: 616320
HGNC: 14169
Ensembl: ENSG00000180185
Variants:
dbSNP: 81889
ClinVar: 81889
TCGA: ENSG00000180185
COSMIC: FAHD1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000180185 | ENST00000382666 | Q6P587 |
| ENSG00000180185 | ENST00000382668 | Q6P587 |
| ENSG00000180185 | ENST00000427358 | Q6P587 |
| ENSG00000180185 | ENST00000615972 | Q6P587 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Tyrosine metabolism | KEGG | ko00350 |
| Tyrosine metabolism | KEGG | hsa00350 |
| Metabolic pathways | KEGG | hsa01100 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38649439 | 2024 | Mitochondrial enzyme FAHD1 reduces ROS in osteosarcoma. | 0 |
| 38649439 | 2024 | Mitochondrial enzyme FAHD1 reduces ROS in osteosarcoma. | 0 |
| 32068790 | 2020 | Structural and functional comparison of fumarylacetoacetate domain containing protein 1 in human and mouse. | 2 |
| 32068790 | 2020 | Structural and functional comparison of fumarylacetoacetate domain containing protein 1 in human and mouse. | 2 |
| 30055189 | 2019 | Oxaloacetate decarboxylase FAHD1 - a new regulator of mitochondrial function and senescence. | 14 |
| 30055189 | 2019 | Oxaloacetate decarboxylase FAHD1 - a new regulator of mitochondrial function and senescence. | 14 |
| 30348641 | 2018 | Structural basis for the bi-functionality of human oxaloacetate decarboxylase FAHD1. | 9 |
| 30348641 | 2018 | Structural basis for the bi-functionality of human oxaloacetate decarboxylase FAHD1. | 9 |
| 28286170 | 2017 | Depletion of oxaloacetate decarboxylase FAHD1 inhibits mitochondrial electron transport and induces cellular senescence in human endothelial cells. | 17 |
| 28286170 | 2017 | Depletion of oxaloacetate decarboxylase FAHD1 inhibits mitochondrial electron transport and induces cellular senescence in human endothelial cells. | 17 |
| 25575590 | 2015 | Identification of FAH domain-containing protein 1 (FAHD1) as oxaloacetate decarboxylase. | 22 |
| 26266933 | 2015 | FAH domain containing protein 1 (FAHD-1) is required for mitochondrial function and locomotion activity in C. elegans. | 10 |
| 25575590 | 2015 | Identification of FAH domain-containing protein 1 (FAHD1) as oxaloacetate decarboxylase. | 22 |
| 26266933 | 2015 | FAH domain containing protein 1 (FAHD-1) is required for mitochondrial function and locomotion activity in C. elegans. | 10 |
| 21878618 | 2011 | Identification of human fumarylacetoacetate hydrolase domain-containing protein 1 (FAHD1) as a novel mitochondrial acylpyruvase. | 22 |
Citation
Dessen P
FAHD1 (fumarylacetoacetate hydrolase domain containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/62976/fahd1-(fumarylacetoacetate-hydrolase-domain-containing-1)
