FAM3A (FAM3 metabolism regulating signaling molecule A)

2014-11-01  

Identity

HGNC
LOCATION
Xq28
LOCUSID
ALIAS
2.19,DLD,DXS560S,XAP-7
FUSION GENES

Other Information

Locus ID:

NCBI: 60343
MIM: 300492
HGNC: 13749
Ensembl: ENSG00000071889

Variants:

dbSNP: 60343
ClinVar: 60343
TCGA: ENSG00000071889
COSMIC: FAM3A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000071889ENST00000322269D3DWX8
ENSG00000071889ENST00000359889P98173
ENSG00000071889ENST00000369641Q5HY75
ENSG00000071889ENST00000369643P98173
ENSG00000071889ENST00000393572P98173
ENSG00000071889ENST00000412894F8WB47
ENSG00000071889ENST00000416319F8WD39
ENSG00000071889ENST00000419205P98173
ENSG00000071889ENST00000421517Q9BU27
ENSG00000071889ENST00000426266A6QRH7
ENSG00000071889ENST00000433619F8WCK6
ENSG00000071889ENST00000434658Q9BU27
ENSG00000071889ENST00000440318F8WEM7
ENSG00000071889ENST00000442929A6QRH8
ENSG00000071889ENST00000447601P98173
ENSG00000071889ENST00000449971Q9BU27
ENSG00000071889ENST00000457212F8WEW8
ENSG00000071889ENST00000621967Q9BU27

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
388759572024FAM3A plays a key role in protecting against tubular cell pyroptosis and acute kidney injury.0
389378532024PANX1-mediated ATP release confers FAM3A's suppression effects on hepatic gluconeogenesis and lipogenesis.0
388759572024FAM3A plays a key role in protecting against tubular cell pyroptosis and acute kidney injury.0
389378532024PANX1-mediated ATP release confers FAM3A's suppression effects on hepatic gluconeogenesis and lipogenesis.0
374748852023FAM3A mediates the phenotypic switch of human aortic smooth muscle cells stimulated with oxidised low-density lipoprotein by influencing the PI3K-AKT pathway.0
374748852023FAM3A mediates the phenotypic switch of human aortic smooth muscle cells stimulated with oxidised low-density lipoprotein by influencing the PI3K-AKT pathway.0
319108172020Case report: targeted whole exome sequencing enables the first prenatal diagnosis of the lethal skeletal dysplasia Osteocraniostenosis.5
319108172020Case report: targeted whole exome sequencing enables the first prenatal diagnosis of the lethal skeletal dysplasia Osteocraniostenosis.5
310004202019Endothelial FAM3A positively regulates post-ischaemic angiogenesis.11
310004202019Endothelial FAM3A positively regulates post-ischaemic angiogenesis.11
295327742018Role of Family with Sequence Similarity 3A in High Glucose-induced Oxidative Damage of Human Umbilical Vein Endothelial Cells.1
295327742018Role of Family with Sequence Similarity 3A in High Glucose-induced Oxidative Damage of Human Umbilical Vein Endothelial Cells.1
276880712016Transcriptional regulation analysis of FAM3A gene and its effect on adipocyte differentiation.1
276880712016Transcriptional regulation analysis of FAM3A gene and its effect on adipocyte differentiation.1
248067532014FAM3A activates PI3K p110α/Akt signaling to ameliorate hepatic gluconeogenesis and lipogenesis.51

Citation

Dessen P

FAM3A (FAM3 metabolism regulating signaling molecule A)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63192/fam3a-(fam3-metabolism-regulating-signaling-molecule-a)