Identity
HGNC
LOCATION
2q37.3
LOCUSID
ALIAS
FIR,FRG,PLEKHC3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9855
MIM: 617586
HGNC: 16460
Ensembl: ENSG00000006607
Variants:
dbSNP: 9855
ClinVar: 9855
TCGA: ENSG00000006607
COSMIC: FARP2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447197 | Attention Deficit Disorder with Hyperactivity | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | 29382897 | |
| PA450464 | methylphenidate | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PD | 29382897 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30872454 | 2019 | The Rho family GEF FARP2 is activated by aPKCι to control tight junction formation and polarity. | 7 |
| 30872454 | 2019 | The Rho family GEF FARP2 is activated by aPKCι to control tight junction formation and polarity. | 7 |
| 20062064 | 2010 | Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk. | 114 |
| 20468071 | 2010 | Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts. | 22 |
| 20855867 | 2010 | Inherited genetic susceptibility to monoclonal B-cell lymphocytosis. | 17 |
| 20062064 | 2010 | Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk. | 114 |
| 20468071 | 2010 | Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts. | 22 |
| 20855867 | 2010 | Inherited genetic susceptibility to monoclonal B-cell lymphocytosis. | 17 |
| 12771149 | 2003 | Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK. | 28 |
| 12771149 | 2003 | Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK. | 28 |
Citation
Dessen P
FARP2 (FERM, ARH/RhoGEF and pleckstrin domain protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/63298
