Identity
HGNC
LOCATION
16p11.2
LOCUSID
ALIAS
CXXC11,Fbl19,JHDM1C
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54620
MIM: 609085
HGNC: 25300
Ensembl: ENSG00000099364
Variants:
dbSNP: 54620
ClinVar: 54620
TCGA: ENSG00000099364
COSMIC: FBXL19
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164713366 | Tumor necrosis factor alpha (TNF-alpha) inhibitors | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PD | 26194362 | |
| PA445451 | Psoriasis | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | 26194362 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34278444 | 2021 | FBXL19‑AS1 promotes the progression of nasopharyngeal carcinoma by acting as a competing endogenous RNA to sponge miR‑431 and upregulate PBOV1. | 1 |
| 34278444 | 2021 | FBXL19‑AS1 promotes the progression of nasopharyngeal carcinoma by acting as a competing endogenous RNA to sponge miR‑431 and upregulate PBOV1. | 1 |
| 31566718 | 2020 | Long noncoding RNA FBXL19-AS1 induces tumor growth and metastasis by sponging miR-203a-3p in lung adenocarcinoma. | 14 |
| 31566718 | 2020 | Long noncoding RNA FBXL19-AS1 induces tumor growth and metastasis by sponging miR-203a-3p in lung adenocarcinoma. | 14 |
| 24684802 | 2014 | F-box protein complex FBXL19 regulates TGFβ1-induced E-cadherin down-regulation by mediating Rac3 ubiquitination and degradation. | 34 |
| 24684802 | 2014 | F-box protein complex FBXL19 regulates TGFβ1-induced E-cadherin down-regulation by mediating Rac3 ubiquitination and degradation. | 34 |
| 20953189 | 2010 | Genome-wide association analysis identifies three psoriasis susceptibility loci. | 143 |
| 20953189 | 2010 | Genome-wide association analysis identifies three psoriasis susceptibility loci. | 143 |
Citation
Dessen P
FBXL19 (F-box and leucine rich repeat protein 19)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/63315/fbxl19-(f-box-and-leucine-rich-repeat-protein-19)
