Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26233
MIM: 609076
HGNC: 13603
Ensembl: ENSG00000182325
Variants:
dbSNP: 26233
ClinVar: 26233
TCGA: ENSG00000182325
COSMIC: FBXL6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000182325 | ENST00000331890 | Q8N531 |
| ENSG00000182325 | ENST00000455319 | Q8N531 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35606330 | 2023 | FBXL6 is dysregulated in keloids and promotes keloid fibroblast growth by inducing c-Myc expression. | 3 |
| 37267103 | 2023 | The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins. | 0 |
| 35606330 | 2023 | FBXL6 is dysregulated in keloids and promotes keloid fibroblast growth by inducing c-Myc expression. | 3 |
| 37267103 | 2023 | The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins. | 0 |
| 33568778 | 2021 | FBXL6 degrades phosphorylated p53 to promote tumor growth. | 14 |
| 33568778 | 2021 | FBXL6 degrades phosphorylated p53 to promote tumor growth. | 14 |
| 32576198 | 2020 | FBXL6 governs c-MYC to promote hepatocellular carcinoma through ubiquitination and stabilization of HSP90AA1. | 28 |
| 32576198 | 2020 | FBXL6 governs c-MYC to promote hepatocellular carcinoma through ubiquitination and stabilization of HSP90AA1. | 28 |
| 18426905 | 2008 | Downregulation of vertebrate Tel (ETV6) and Drosophila Yan is facilitated by an evolutionarily conserved mechanism of F-box-mediated ubiquitination. | 17 |
| 18426905 | 2008 | Downregulation of vertebrate Tel (ETV6) and Drosophila Yan is facilitated by an evolutionarily conserved mechanism of F-box-mediated ubiquitination. | 17 |
Citation
Dessen P
FBXL6 (F-box and leucine rich repeat protein 6)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/63319/fbxl6-(f-box-and-leucine-rich-repeat-protein-6)
