FBXO15 (F-box protein 15)

2014-11-01  

Identity

HGNC
FBXO15
LOCATION
18q22.3
LOCUSID
201456
ALIAS
FBX15
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 201456
MIM: 609093
HGNC: 13617
Ensembl: ENSG00000141665

Variants:

dbSNP: 201456
ClinVar: 201456
TCGA: ENSG00000141665
COSMIC: FBXO15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000141665ENST00000419743Q8NCQ5
ENSG00000141665ENST00000578399J3KRT3
ENSG00000141665ENST00000579517J3QKV0
ENSG00000141665ENST00000580088J3KRQ6
ENSG00000141665ENST00000580552J3KS84
ENSG00000141665ENST00000581214J3KRS5
ENSG00000141665ENST00000582526J3QLF9
ENSG00000141665ENST00000583443J3QRE7
ENSG00000141665ENST00000585174J3QL50
ENSG00000141665ENST00000648529A0A3B3IRP1

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

References

Pubmed IDYearTitleCitations
340835072021FBXO15 plays a critical suppressive functional role in regulation of breast cancer progression.1
340835072021FBXO15 plays a critical suppressive functional role in regulation of breast cancer progression.1
234650772013FBXO15 regulates P-glycoprotein/ABCB1 expression through the ubiquitin--proteasome pathway in cancer cells.35
234650772013FBXO15 regulates P-glycoprotein/ABCB1 expression through the ubiquitin--proteasome pathway in cancer cells.35

Citation

Dessen P

FBXO15 (F-box protein 15)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63321/fbxo15-(f-box-protein-15)