Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54461
MIM: 609072
HGNC: 13613
Ensembl: ENSG00000159069
Variants:
dbSNP: 54461
ClinVar: 54461
TCGA: ENSG00000159069
COSMIC: FBXW5
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34368969 | 2021 | SCF(Fbxw5) targets kinesin-13 proteins to facilitate ciliogenesis. | 5 |
| 34368969 | 2021 | SCF(Fbxw5) targets kinesin-13 proteins to facilitate ciliogenesis. | 5 |
| 30596474 | 2018 | The ULK1-FBXW5-SEC23B nexus controls autophagy. | 36 |
| 30596474 | 2018 | The ULK1-FBXW5-SEC23B nexus controls autophagy. | 36 |
| 24444419 | 2014 | Tnfaip8 l1/Oxi-β binds to FBXW5, increasing autophagy through activation of TSC2 in a Parkinson's disease model. | 28 |
| 24444419 | 2014 | Tnfaip8 l1/Oxi-β binds to FBXW5, increasing autophagy through activation of TSC2 in a Parkinson's disease model. | 28 |
| 23314863 | 2013 | SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression. | 17 |
| 24082123 | 2013 | CRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growth. | 34 |
| 23314863 | 2013 | SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression. | 17 |
| 24082123 | 2013 | CRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growth. | 34 |
| 22910413 | 2012 | Fbxw5 suppresses nuclear c-Myb activity via DDB1-Cul4-Rbx1 ligase-mediated sumoylation. | 7 |
| 22910413 | 2012 | Fbxw5 suppresses nuclear c-Myb activity via DDB1-Cul4-Rbx1 ligase-mediated sumoylation. | 7 |
| 21725316 | 2011 | The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication. | 80 |
| 21725316 | 2011 | The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication. | 80 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
Citation
Dessen P
FBXW5 (F-box and WD repeat domain containing 5)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/63343/fbxw5-(f-box-and-wd-repeat-domain-containing-5)
