FCF1 (FCF1 rRNA-processing protein)

2014-11-01  

Identity

HGNC
FCF1
LOCATION
14q24.3
LOCUSID
51077
ALIAS
Bka,C14orf111,CGI-35,UTP24
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51077
HGNC: 20220
Ensembl: ENSG00000119616

Variants:

dbSNP: 51077
ClinVar: 51077
TCGA: ENSG00000119616
COSMIC: FCF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000119616ENST00000341162Q9Y324
ENSG00000119616ENST00000341162Q4FZ45
ENSG00000119616ENST00000534938G3V1S4
ENSG00000119616ENST00000553615G3V5S9
ENSG00000119616ENST00000553673G3V5D2
ENSG00000119616ENST00000554064G3V5L8
ENSG00000119616ENST00000554590G3V2M5
ENSG00000119616ENST00000556814G3V3N8

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Ribosome biogenesis in eukaryotesKEGGko03008
Ribosome biogenesis in eukaryotesKEGGhsa03008
Gene ExpressionREACTOMER-HSA-74160
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA modification in the nucleus and cytosolREACTOMER-HSA-6790901
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
262375812015hUTP24 is essential for processing of the human rRNA precursor at site A1, but not at site A0.18
262375812015hUTP24 is essential for processing of the human rRNA precursor at site A1, but not at site A0.18

Citation

Dessen P

FCF1 (FCF1 rRNA-processing protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63346/fcf1-(fcf1-rrna-processing-protein)