FLRT3 (fibronectin leucine rich transmembrane protein 3)

2014-11-01  

Identity

HGNC
LOCATION
20p12.1
LOCUSID
ALIAS
HH21

Other Information

Locus ID:

NCBI: 23767
MIM: 604808
HGNC: 3762
Ensembl: ENSG00000125848

Variants:

dbSNP: 23767
ClinVar: 23767
TCGA: ENSG00000125848
COSMIC: FLRT3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125848ENST00000341420Q9NZU0
ENSG00000125848ENST00000378053Q9NZU0

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by FGFRREACTOMER-HSA-190236
Signaling by FGFR1REACTOMER-HSA-5654736
Downstream signaling of activated FGFR1REACTOMER-HSA-5654687

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
385097272024FLRT3 and TGF-β/SMAD4 signalling: Impacts on apoptosis, autophagy and ion channels in supraventricular tachycardia.1
385097272024FLRT3 and TGF-β/SMAD4 signalling: Impacts on apoptosis, autophagy and ion channels in supraventricular tachycardia.1
355602242022TGF-β-Induced FLRT3 Attenuation Is Essential for Cancer-Associated Fibroblast-Mediated Epithelial-Mesenchymal Transition in Colorectal Cancer.13
355602242022TGF-β-Induced FLRT3 Attenuation Is Essential for Cancer-Associated Fibroblast-Mediated Epithelial-Mesenchymal Transition in Colorectal Cancer.13
337116692021Variants in FLRT3 and SLC35E2B identified using exome sequencing in seven high myopia families from Central Europe.6
337116692021Variants in FLRT3 and SLC35E2B identified using exome sequencing in seven high myopia families from Central Europe.6
274219692017Adipose Gene Expression Profile Changes With Lung Allograft Reperfusion.5
274219692017Adipose Gene Expression Profile Changes With Lung Allograft Reperfusion.5
262350302015Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion.69
262350302015Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion.69
224052012012FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development.132
224052012012FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development.132
185938712008Lack of C20orf133 and FLRT3 mutations in 43 patients with Kabuki syndrome in Japan.2
185938712008Lack of C20orf133 and FLRT3 mutations in 43 patients with Kabuki syndrome in Japan.2

Citation

Dessen P

FLRT3 (fibronectin leucine rich transmembrane protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63541/flrt3-(fibronectin-leucine-rich-transmembrane-protein-3)