FPGT (fucose-1-phosphate guanylyltransferase)

2014-11-01  

Identity

HGNC
LOCATION
1p31.1
LOCUSID
ALIAS
GFPP
FUSION GENES

Other Information

Locus ID:

NCBI: 8790
MIM: 603609
HGNC: 3825
Ensembl: ENSG00000254685

Variants:

dbSNP: 8790
ClinVar: 8790
TCGA: ENSG00000254685
COSMIC: FPGT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000254685ENST00000370894O14772
ENSG00000254685ENST00000370894A0A0S2Z4P4
ENSG00000254685ENST00000370898O14772
ENSG00000254685ENST00000467578E9PMK0
ENSG00000254685ENST00000472069H0YDF0
ENSG00000254685ENST00000482102E9PMM4
ENSG00000254685ENST00000529485E9PK10
ENSG00000254685ENST00000534056O14772

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Fructose and mannose metabolismKEGGko00051
Amino sugar and nucleotide sugar metabolismKEGGko00520
Fructose and mannose metabolismKEGGhsa00051
Amino sugar and nucleotide sugar metabolismKEGGhsa00520
Metabolic pathwaysKEGGhsa01100
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent proteinREACTOMER-HSA-446193
Synthesis of substrates in N-glycan biosythesisREACTOMER-HSA-446219
GDP-fucose biosynthesisREACTOMER-HSA-6787639

References

Pubmed IDYearTitleCitations
165824932006Purification, crystallization and preliminary X-ray characterization of the human GTP fucose pyrophosphorylase.1
165824932006Purification, crystallization and preliminary X-ray characterization of the human GTP fucose pyrophosphorylase.1
160865882005Substrate discrimination by the human GTP fucose pyrophosphorylase.23
161850852005Identification of catalytic amino acids in the human GTP fucose pyrophosphorylase active site.17
160865882005Substrate discrimination by the human GTP fucose pyrophosphorylase.23
161850852005Identification of catalytic amino acids in the human GTP fucose pyrophosphorylase active site.17

Citation

Dessen P

FPGT (fucose-1-phosphate guanylyltransferase)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63579/fpgt-(fucose-1-phosphate-guanylyltransferase)