FRY (FRY microtubule binding protein)

2014-11-01  

Identity

HGNC
FRY
LOCATION
13q13.1
LOCUSID
10129
ALIAS
13CDNA73,214K23.2,C13orf14,CG003,bA207N4.2,bA37E23.1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10129
MIM: 614818
HGNC: 20367
Ensembl: ENSG00000073910

Variants:

dbSNP: 10129
ClinVar: 10129
TCGA: ENSG00000073910
COSMIC: FRY

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000073910ENST00000380250A0A0C4DFX2
ENSG00000073910ENST00000436046B1ALA1
ENSG00000073910ENST00000477712H0YE00
ENSG00000073910ENST00000542859Q5TBA9
ENSG00000073910ENST00000642040A0A286YFA9
ENSG00000073910ENST00000643293A0A2R8Y7Y8
ENSG00000073910ENST00000645780A0A2R8YCY2
ENSG00000073910ENST00000647500A0A2R8Y5V8

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
238869462013Furry promotes acetylation of microtubules in the mitotic spindle by inhibition of SIRT2 tubulin deacetylase.33
238869462013Furry promotes acetylation of microtubules in the mitotic spindle by inhibition of SIRT2 tubulin deacetylase.33
227534162012Furry protein promotes aurora A-mediated Polo-like kinase 1 activation.22
227534162012Furry protein promotes aurora A-mediated Polo-like kinase 1 activation.22
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
193279962009MST2- and Furry-mediated activation of NDR1 kinase is critical for precise alignment of mitotic chromosomes.64
197732792009Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.9
193279962009MST2- and Furry-mediated activation of NDR1 kinase is critical for precise alignment of mitotic chromosomes.64
197732792009Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.9

Citation

Dessen P

FRY (FRY microtubule binding protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63606