Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57818
MIM: 608058
HGNC: 28906
Ensembl: ENSG00000152254
Variants:
dbSNP: 57818
ClinVar: 57818
TCGA: ENSG00000152254
COSMIC: G6PC2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000152254 | ENST00000282075 | Q9NQR9 |
| ENSG00000152254 | ENST00000375363 | Q9NQR9 |
| ENSG00000152254 | ENST00000421979 | C9IYU7 |
| ENSG00000152254 | ENST00000429379 | Q9NQR9 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38095063 | 2024 | Identification of structural motifs critical for human G6PC2 function informed by sequence analysis and an AlphaFold2-predicted model. | 0 |
| 38095063 | 2024 | Identification of structural motifs critical for human G6PC2 function informed by sequence analysis and an AlphaFold2-predicted model. | 0 |
| 37855366 | 2023 | G6PC1 and G6PC2 influence G6P flux but not HSD11B1 activity. | 1 |
| 37855366 | 2023 | G6PC1 and G6PC2 influence G6P flux but not HSD11B1 activity. | 1 |
| 35277194 | 2022 | G6PC indicated poor prognosis in cervical cancer and promoted cervical carcinogenesis in vitro and in vivo. | 9 |
| 35534112 | 2022 | Mutations in G6PC2 gene with increased risk for development of type 2 diabetes: Understanding via computational approach. | 4 |
| 35657990 | 2022 | Additive genetic effect of GCKR, G6PC2, and SLC30A8 variants on fasting glucose levels and risk of type 2 diabetes. | 2 |
| 35277194 | 2022 | G6PC indicated poor prognosis in cervical cancer and promoted cervical carcinogenesis in vitro and in vivo. | 9 |
| 35534112 | 2022 | Mutations in G6PC2 gene with increased risk for development of type 2 diabetes: Understanding via computational approach. | 4 |
| 35657990 | 2022 | Additive genetic effect of GCKR, G6PC2, and SLC30A8 variants on fasting glucose levels and risk of type 2 diabetes. | 2 |
| 33842983 | 2021 | Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose. | 7 |
| 34128214 | 2021 | Haplotypes of the genes (GCK and G6PC2) underlying the glucose/glucose-6-phosphate cycle are associated with pancreatic beta cell glucose sensitivity in patients with newly diagnosed type 2 diabetes from the VNDS study (VNDS 11). | 0 |
| 33842983 | 2021 | Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose. | 7 |
| 34128214 | 2021 | Haplotypes of the genes (GCK and G6PC2) underlying the glucose/glucose-6-phosphate cycle are associated with pancreatic beta cell glucose sensitivity in patients with newly diagnosed type 2 diabetes from the VNDS study (VNDS 11). | 0 |
| 32213654 | 2020 | Pancreatic islet beta cell-specific deletion of G6pc2 reduces fasting blood glucose. | 13 |
Citation
Dessen P
G6PC2 (glucose-6-phosphatase catalytic subunit 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/63639/g6pc2-(glucose-6-phosphatase-catalytic-subunit-2)
