Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2559
MIM: 137143
HGNC: 4080
Ensembl: ENSG00000145863
Variants:
dbSNP: 2559
ClinVar: 2559
TCGA: ENSG00000145863
COSMIC: GABRA6
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164713257 | Selective serotonin reuptake inhibitors | Chemical | ClinicalAnnotation | associated | PD | 23394390 | |
| PA447321 | Depressive Disorder, Major | Disease | ClinicalAnnotation | associated | PD | 23394390 | |
| PA451866 | venlafaxine | Chemical | ClinicalAnnotation | associated | PD | 23394390 | |
| PA452229 | antidepressants | Chemical | ClinicalAnnotation | associated | PD | 23394390 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34740144 | 2021 | GABRA1 and GABRA6 gene mutations in idiopathic generalized epilepsy patients. | 7 |
| 34740144 | 2021 | GABRA1 and GABRA6 gene mutations in idiopathic generalized epilepsy patients. | 7 |
| 29018204 | 2017 | A new stress sensor and risk factor for suicide: the T allele of the functional genetic variant in the GABRA6 gene. | 7 |
| 29018204 | 2017 | A new stress sensor and risk factor for suicide: the T allele of the functional genetic variant in the GABRA6 gene. | 7 |
| 25974322 | 2015 | Association of TMEM132D, COMT, and GABRA6 genotypes with cingulate, frontal cortex and hippocampal emotional processing in panic and major depressive disorder. | 14 |
| 26535938 | 2015 | A multilevel prediction of physiological response to challenge: Interactions among child maltreatment, neighborhood crime, endothelial nitric oxide synthase gene (eNOS), and GABA(A) receptor subunit alpha-6 gene (GABRA6). | 3 |
| 25974322 | 2015 | Association of TMEM132D, COMT, and GABRA6 genotypes with cingulate, frontal cortex and hippocampal emotional processing in panic and major depressive disorder. | 14 |
| 26535938 | 2015 | A multilevel prediction of physiological response to challenge: Interactions among child maltreatment, neighborhood crime, endothelial nitric oxide synthase gene (eNOS), and GABA(A) receptor subunit alpha-6 gene (GABRA6). | 3 |
| 25088614 | 2014 | Association of GABRA6 1519 T>C (rs3219151) and Synapsin II (rs37733634) gene polymorphisms with the development of idiopathic generalized epilepsy. | 10 |
| 25088614 | 2014 | Association of GABRA6 1519 T>C (rs3219151) and Synapsin II (rs37733634) gene polymorphisms with the development of idiopathic generalized epilepsy. | 10 |
| 23332465 | 2013 | Polymorphisms in microRNA target sites influence susceptibility to schizophrenia by altering the binding of miRNAs to their targets. | 19 |
| 23332465 | 2013 | Polymorphisms in microRNA target sites influence susceptibility to schizophrenia by altering the binding of miRNAs to their targets. | 19 |
| 21902679 | 2012 | The role of genetic variability in the SLC6A4, BDNF and GABRA6 genes in anxiety-related traits. | 14 |
| 21902679 | 2012 | The role of genetic variability in the SLC6A4, BDNF and GABRA6 genes in anxiety-related traits. | 14 |
| 21041608 | 2011 | Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up. | 58 |
Citation
Dessen P
GABRA6 (gamma-aminobutyric acid type A receptor subunit alpha6)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/63650/
