GADL1 (glutamate decarboxylase like 1)

2014-11-01  

Identity

HGNC
GADL1
LOCATION
3p24.1
LOCUSID
339896
ALIAS
ADC,CSADC,HuADC,HuCSADC
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 339896
MIM: 615601
HGNC: 27949
Ensembl: ENSG00000144644

Variants:

dbSNP: 339896
ClinVar: 339896
TCGA: ENSG00000144644
COSMIC: GADL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144644ENST00000282538Q6ZQY3
ENSG00000144644ENST00000454381Q6ZQY3

Expression (GTEx)

0
1
2
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
beta-Alanine metabolismKEGGko00410
Taurine and hypotaurine metabolismKEGGko00430
Pantothenate and CoA biosynthesisKEGGko00770
beta-Alanine metabolismKEGGhsa00410
Taurine and hypotaurine metabolismKEGGhsa00430
Pantothenate and CoA biosynthesisKEGGhsa00770
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Amino acid synthesis and interconversion (transamination)REACTOMER-HSA-70614

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
309233252019Effects of GADL1 overexpression on cell migration and the associated morphological changes.3
309233252019Effects of GADL1 overexpression on cell migration and the associated morphological changes.3
282147792017Lithium response in bipolar disorder: No difference in GADL1 gene expression between cell lines from excellent-responders and non-responders.3
282147792017Lithium response in bipolar disorder: No difference in GADL1 gene expression between cell lines from excellent-responders and non-responders.3
254154572015GADL1 gene polymorphisms and lithium response in bipolar I disorder: lack of association from an Indian population.9
263273102015Mammalian CSAD and GADL1 have distinct biochemical properties and patterns of brain expression.13
254154572015GADL1 gene polymorphisms and lithium response in bipolar I disorder: lack of association from an Indian population.9
263273102015Mammalian CSAD and GADL1 have distinct biochemical properties and patterns of brain expression.13
243690492014Variant GADL1 and response to lithium therapy in bipolar I disorder.47
243690492014Variant GADL1 and response to lithium therapy in bipolar I disorder.47

Citation

Dessen P

GADL1 (glutamate decarboxylase like 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63659/chromosome-explorer/gene-explorer/