GADL1 (glutamate decarboxylase like 1)

2014-11-01  

Identity

HGNC
LOCATION
3p24.1
LOCUSID
ALIAS
ADC,CSADC,HuADC,HuCSADC
FUSION GENES

Other Information

Locus ID:

NCBI: 339896
MIM: 615601
HGNC: 27949
Ensembl: ENSG00000144644

Variants:

dbSNP: 339896
ClinVar: 339896
TCGA: ENSG00000144644
COSMIC: GADL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144644ENST00000282538Q6ZQY3
ENSG00000144644ENST00000454381Q6ZQY3

Expression (GTEx)

0
1
2

Pathways

PathwaySourceExternal ID
beta-Alanine metabolismKEGGko00410
Taurine and hypotaurine metabolismKEGGko00430
Pantothenate and CoA biosynthesisKEGGko00770
beta-Alanine metabolismKEGGhsa00410
Taurine and hypotaurine metabolismKEGGhsa00430
Pantothenate and CoA biosynthesisKEGGhsa00770
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Amino acid synthesis and interconversion (transamination)REACTOMER-HSA-70614

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
263273102015Mammalian CSAD and GADL1 have distinct biochemical properties and patterns of brain expression.7
243690492014Variant GADL1 and response to lithium therapy in bipolar I disorder.0
254154572015GADL1 gene polymorphisms and lithium response in bipolar I disorder: lack of association from an Indian population.0
282147792017Lithium response in bipolar disorder: No difference in GADL1 gene expression between cell lines from excellent-responders and non-responders.0

Citation

Dessen P

GADL1 (glutamate decarboxylase like 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63659/gadl1-(glutamate-decarboxylase-like-1)