Identity
HGNC
LOCATION
15q15.1
LOCUSID
ALIAS
GFRP,HsT16933,P35
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2644
MIM: 602437
HGNC: 4194
Ensembl: ENSG00000137880
Variants:
dbSNP: 2644
ClinVar: 2644
TCGA: ENSG00000137880
COSMIC: GCHFR
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33387654 | 2021 | Biophysical and structural investigation of the regulation of human GTP cyclohydrolase I by its regulatory protein GFRP. | 1 |
| 33387654 | 2021 | Biophysical and structural investigation of the regulation of human GTP cyclohydrolase I by its regulatory protein GFRP. | 1 |
| 33229582 | 2020 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I. | 3 |
| 33229582 | 2020 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I. | 3 |
| 20351752 | 2011 | A polymorphism of the GTP-cyclohydrolase I feedback regulator gene alters transcriptional activity and may affect response to SSRI antidepressants. | 2 |
| 20351752 | 2011 | A polymorphism of the GTP-cyclohydrolase I feedback regulator gene alters transcriptional activity and may affect response to SSRI antidepressants. | 2 |
| 20351752 | 2011 | A polymorphism of the GTP-cyclohydrolase I feedback regulator gene alters transcriptional activity and may affect response to SSRI antidepressants. | 2 |
| 20351752 | 2011 | A polymorphism of the GTP-cyclohydrolase I feedback regulator gene alters transcriptional activity and may affect response to SSRI antidepressants. | 2 |
| 19926872 | 2010 | GTP cyclohydrolase I phosphorylation and interaction with GTP cyclohydrolase feedback regulatory protein provide novel regulation of endothelial tetrahydrobiopterin and nitric oxide. | 31 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 19926872 | 2010 | GTP cyclohydrolase I phosphorylation and interaction with GTP cyclohydrolase feedback regulatory protein provide novel regulation of endothelial tetrahydrobiopterin and nitric oxide. | 31 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 19101819 | 2009 | H(2)O(2) increases de novo synthesis of (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin via GTP cyclohydrolase I and its feedback regulatory protein in vitiligo. | 4 |
| 19674121 | 2009 | Examination of tetrahydrobiopterin pathway genes in autism. | 7 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
Citation
Dessen P
GCHFR (GTP cyclohydrolase I feedback regulator)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/63734/gchfr-(gtp-cyclohydrolase-i-feedback-regulator)
