GDPD3 (glycerophosphodiester phosphodiesterase domain containing 3)

2014-11-01  

Identity

HGNC
LOCATION
16p11.2
LOCUSID
ALIAS
GDE7

Other Information

Locus ID:

NCBI: 79153
MIM: 616318
HGNC: 28638
Ensembl: ENSG00000102886

Variants:

dbSNP: 79153
ClinVar: 79153
TCGA: ENSG00000102886
COSMIC: GDPD3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102886ENST00000406256Q7L5L3
ENSG00000102886ENST00000566434H3BPX3
ENSG00000102886ENST00000566613H3BMN9

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
PI MetabolismREACTOMER-HSA-1483255
Glycerophospholipid catabolismREACTOMER-HSA-6814848

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371937622023GDE7 produces cyclic phosphatidic acid in the ER lumen functioning as a lysophospholipid mediator.3
371937622023GDE7 produces cyclic phosphatidic acid in the ER lumen functioning as a lysophospholipid mediator.3
346730202021Development of a selective fluorescence-based enzyme assay for glycerophosphodiesterase family members GDE4 and GDE7.2
346730202021Development of a selective fluorescence-based enzyme assay for glycerophosphodiesterase family members GDE4 and GDE7.2
324303162020Human GDPD3 overexpression promotes liver steatosis by increasing lysophosphatidic acid production and fatty acid uptake.10
324303162020Human GDPD3 overexpression promotes liver steatosis by increasing lysophosphatidic acid production and fatty acid uptake.10

Citation

Dessen P

GDPD3 (glycerophosphodiester phosphodiesterase domain containing 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63748/gdpd3-(glycerophosphodiester-phosphodiesterase-domain-containing-3)