GFRAL (GDNF family receptor alpha like)

2014-11-01  

Identity

HGNC
LOCATION
6p12.1
LOCUSID
ALIAS
C6orf144,GRAL,UNQ9356,bA360D14.1
FUSION GENES

Other Information

Locus ID:

NCBI: 389400
MIM: 617837
HGNC: 32789
Ensembl: ENSG00000187871

Variants:

dbSNP: 389400
ClinVar: 389400
TCGA: ENSG00000187871
COSMIC: GFRAL

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000187871ENST00000340465Q6UXV0

Expression (GTEx)

0
1

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382546382023GDF-15 Inhibits ADP-Induced Human Platelet Aggregation through the GFRAL/RET Signaling Complex.0
382546382023GDF-15 Inhibits ADP-Induced Human Platelet Aggregation through the GFRAL/RET Signaling Complex.0
338524272021Genome-wide association and transcriptome analysis suggests total serum ghrelin to be linked with GFRAL.4
338524272021Genome-wide association and transcriptome analysis suggests total serum ghrelin to be linked with GFRAL.4
326613912020Antibody-mediated inhibition of GDF15-GFRAL activity reverses cancer cachexia in mice.104
332018382020Upregulated GDF-15 expression facilitates pancreatic ductal adenocarcinoma progression through orphan receptor GFRAL.17
326613912020Antibody-mediated inhibition of GDF15-GFRAL activity reverses cancer cachexia in mice.104
332018382020Upregulated GDF-15 expression facilitates pancreatic ductal adenocarcinoma progression through orphan receptor GFRAL.17

Citation

Dessen P

GFRAL (GDNF family receptor alpha like)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63761/gfral-(gdnf-family-receptor-alpha-like)