Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64599
MIM: 612064
HGNC: 9126
Ensembl: ENSG00000146830
Variants:
dbSNP: 64599
ClinVar: 64599
TCGA: ENSG00000146830
COSMIC: GIGYF1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000146830 | ENST00000275732 | O75420 |
| ENSG00000146830 | ENST00000646601 | O75420 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36924980 | 2023 | Genetic Ablation of GIGYF1, Associated With Autism, Causes Behavioral and Neurodevelopmental Defects in Zebrafish and Mice. | 1 |
| 37484805 | 2023 | Low Expression of GIGYF1 Inhibits Metastasis, Proliferation, and Promotes Apoptosis and Autophagy of Gastric Cancer Cells. | 1 |
| 36924980 | 2023 | Genetic Ablation of GIGYF1, Associated With Autism, Causes Behavioral and Neurodevelopmental Defects in Zebrafish and Mice. | 1 |
| 37484805 | 2023 | Low Expression of GIGYF1 Inhibits Metastasis, Proliferation, and Promotes Apoptosis and Autophagy of Gastric Cancer Cells. | 1 |
| 36189799 | 2022 | GIGYF1-disturbed IGF-1R recycling: a potential contributor to autism spectrum disorder pathogenesis? | 1 |
| 36189799 | 2022 | GIGYF1-disturbed IGF-1R recycling: a potential contributor to autism spectrum disorder pathogenesis? | 1 |
| 34234147 | 2021 | GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health. | 15 |
| 34732801 | 2021 | Gene-level analysis of rare variants in 379,066 whole exome sequences identifies an association of GIGYF1 loss of function with type 2 diabetes. | 18 |
| 34234147 | 2021 | GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health. | 15 |
| 34732801 | 2021 | Gene-level analysis of rare variants in 379,066 whole exome sequences identifies an association of GIGYF1 loss of function with type 2 diabetes. | 18 |
| 33053355 | 2020 | 4EHP and GIGYF1/2 Mediate Translation-Coupled Messenger RNA Decay. | 27 |
| 33053355 | 2020 | 4EHP and GIGYF1/2 Mediate Translation-Coupled Messenger RNA Decay. | 27 |
| 17672918 | 2007 | Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. | 20 |
| 17672918 | 2007 | Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. | 20 |
Citation
Dessen P
GIGYF1 (GRB10 interacting GYF protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/63780/gigyf1-(grb10-interacting-gyf-protein-1)
