GK (glycerol kinase)

2014-11-01  

Identity

HGNC
LOCATION
Xp21.2
LOCUSID
ALIAS
GK1,GKD
FUSION GENES

Other Information

Locus ID:

NCBI: 2710
MIM: 300474
HGNC: 4289
Ensembl: ENSG00000198814

Variants:

dbSNP: 2710
ClinVar: 2710
TCGA: ENSG00000198814
COSMIC: GK

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198814ENST00000378938H7BYD2
ENSG00000198814ENST00000378941A6NP46
ENSG00000198814ENST00000378943P32189
ENSG00000198814ENST00000378945P32189
ENSG00000198814ENST00000378946P32189
ENSG00000198814ENST00000425166H7C2A0
ENSG00000198814ENST00000427190P32189
ENSG00000198814ENST00000471362F8WBI8
ENSG00000198814ENST00000479048F8WDA9
ENSG00000198814ENST00000481024F8WC39
ENSG00000198814ENST00000487652F8WF44
ENSG00000198814ENST00000488296H7C5F6

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Glycerolipid metabolismKEGGko00561
PPAR signaling pathwayKEGGko03320
Glycerolipid metabolismKEGGhsa00561
PPAR signaling pathwayKEGGhsa03320
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Triglyceride BiosynthesisREACTOMER-HSA-75109

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
383659532024Glycerol kinase enzyme is a prognostic predictor in esophageal carcinoma and is associated with immune cell infiltration.0
383659532024Glycerol kinase enzyme is a prognostic predictor in esophageal carcinoma and is associated with immune cell infiltration.0
370217752023Expression and characterisation of human glycerol kinase: the role of solubilising agents and molecular chaperones.3
370217752023Expression and characterisation of human glycerol kinase: the role of solubilising agents and molecular chaperones.3
318132312020Glycerol kinase enhances hepatic lipid metabolism by repressing nuclear receptor subfamily 4 group A1 in the nucleus.2
318132312020Glycerol kinase enhances hepatic lipid metabolism by repressing nuclear receptor subfamily 4 group A1 in the nucleus.2
270870232016Complex Glycerol Kinase Deficiency and Adrenocortical Insufficiency in Two Neonates.3
270870232016Complex Glycerol Kinase Deficiency and Adrenocortical Insufficiency in Two Neonates.3
201102162010The diagnostic difficulties of complex glycerol kinase deficiency.4
201102162010The diagnostic difficulties of complex glycerol kinase deficiency.4
186604892008Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.29
186604892008Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.29
165495352006Asymptomatic isolated human glycerol kinase deficiency associated with splice-site mutations and nonsense-mediated decay of mutant RNA.1
165495352006Asymptomatic isolated human glycerol kinase deficiency associated with splice-site mutations and nonsense-mediated decay of mutant RNA.1
158453842005Human and murine glycerol kinase: influence of exon 18 alternative splicing on function.11

Citation

Dessen P

GK (glycerol kinase)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63804/gene-fusions/new-content/