Identity
HGNC
LOCATION
7p21.3
LOCUSID
ALIAS
FAM117C,GCTR,GIG18,TSSN1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 113263
MIM: 614283
HGNC: 18713
Ensembl: ENSG00000106415
Variants:
dbSNP: 113263
ClinVar: 113263
TCGA: ENSG00000106415
COSMIC: GLCCI1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000106415 | ENST00000223145 | Q86VQ1 |
| ENSG00000106415 | ENST00000414914 | H7C2L5 |
| ENSG00000106415 | ENST00000430798 | H7C0Q2 |
| ENSG00000106415 | ENST00000438949 | H7C0B2 |
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10832 | corticosteroids | Chemical | VariantAnnotation | not associated | PD | 27523435 | |
| PA443450 | Asthma | Disease | ClinicalAnnotation, VariantAnnotation | ambiguous | PD | 21991891, 27523435 | |
| PA448681 | budesonide | Chemical | ClinicalAnnotation | associated | PD | 21991891 | |
| PA449661 | flunisolide | Chemical | ClinicalAnnotation | associated | PD | 21991891 | |
| PA449686 | fluticasone propionate | Chemical | ClinicalAnnotation | associated | PD | 21991891 | |
| PA450601 | nedocromil | Chemical | ClinicalAnnotation | associated | PD | 21991891 | |
| PA451749 | triamcinolone | Chemical | ClinicalAnnotation | associated | PD | 21991891 | |
| PA452347 | glucocorticoids | Chemical | ClinicalAnnotation | associated | PD | 21991891 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37553950 | 2023 | Glucocorticoid-Induced Transcript 1(GLCCI1) SNP rs37937 Is Associated With the Risk of Developing Allergic Rhinitis and the Response to Intranasal Corticosteroids in a Chinese Han Population. | 0 |
| 37553950 | 2023 | Glucocorticoid-Induced Transcript 1(GLCCI1) SNP rs37937 Is Associated With the Risk of Developing Allergic Rhinitis and the Response to Intranasal Corticosteroids in a Chinese Han Population. | 0 |
| 31516081 | 2021 | GLCCI1 and STIP1 variants are associated with asthma susceptibility and inhaled corticosteroid response in a Tunisian population. | 5 |
| 33725570 | 2021 | Hsa_circ_001659 serves as a novel diagnostic and prognostic biomarker for colorectal cancer. | 8 |
| 34529984 | 2021 | GLCCI1 gene body methylation in peripheral blood is associated with asthma and asthma severity. | 1 |
| 31516081 | 2021 | GLCCI1 and STIP1 variants are associated with asthma susceptibility and inhaled corticosteroid response in a Tunisian population. | 5 |
| 33725570 | 2021 | Hsa_circ_001659 serves as a novel diagnostic and prognostic biomarker for colorectal cancer. | 8 |
| 34529984 | 2021 | GLCCI1 gene body methylation in peripheral blood is associated with asthma and asthma severity. | 1 |
| 33208131 | 2020 | Effects of STIP1 and GLCCI1 polymorphisms on the risk of childhood asthma and inhaled corticosteroid response in Chinese asthmatic children. | 4 |
| 33208131 | 2020 | Effects of STIP1 and GLCCI1 polymorphisms on the risk of childhood asthma and inhaled corticosteroid response in Chinese asthmatic children. | 4 |
| 30229311 | 2019 | A single-nucleotide polymorphism in a gene modulating glucocorticoid sensitivity is associated with the decline in total lung capacity after lung transplantation. | 2 |
| 30860871 | 2019 | GLCCI1 is a novel protector against glucocorticoid-induced apoptosis in T cells. | 9 |
| 30229311 | 2019 | A single-nucleotide polymorphism in a gene modulating glucocorticoid sensitivity is associated with the decline in total lung capacity after lung transplantation. | 2 |
| 30860871 | 2019 | GLCCI1 is a novel protector against glucocorticoid-induced apoptosis in T cells. | 9 |
| 28488322 | 2018 | Impact of the genetic variants of GLCCI1 on clinical features of asthmatic patients. | 4 |
Citation
Dessen P
GLCCI1 (glucocorticoid induced 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/63813/glcci1-(glucocorticoid-induced-1)
