Identity
HGNC
LOCATION
14q32.13
LOCUSID
ALIAS
C14orf87,FLB4739,GRX5,PR01238,PRO1238,PRSA,SIDBA3,SPAHGC
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51218
MIM: 609588
HGNC: 20134
Ensembl: ENSG00000182512
Variants:
dbSNP: 51218
ClinVar: 51218
TCGA: ENSG00000182512
COSMIC: GLRX5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000182512 | ENST00000331334 | Q86SX6 |
| ENSG00000182512 | ENST00000331334 | A0A384MDT9 |
| ENSG00000182512 | ENST00000557731 | H0YJM6 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32542995 | 2021 | Cluster exchange reactivity of [2Fe-2S]-bridged heterodimeric BOLA1-GLRX5. | 4 |
| 34063696 | 2021 | Molecular Basis of Multiple Mitochondrial Dysfunctions Syndrome 2 Caused by CYS59TYR BOLA3 Mutation. | 5 |
| 34732213 | 2021 | GLRX5-associated [Fe-S] cluster biogenesis disorder: further characterisation of the neurological phenotype and long-term outcome. | 1 |
| 32542995 | 2021 | Cluster exchange reactivity of [2Fe-2S]-bridged heterodimeric BOLA1-GLRX5. | 4 |
| 34063696 | 2021 | Molecular Basis of Multiple Mitochondrial Dysfunctions Syndrome 2 Caused by CYS59TYR BOLA3 Mutation. | 5 |
| 34732213 | 2021 | GLRX5-associated [Fe-S] cluster biogenesis disorder: further characterisation of the neurological phenotype and long-term outcome. | 1 |
| 31724821 | 2020 | A pathway for assembling [4Fe-4S](2+) clusters in mitochondrial iron-sulfur protein biogenesis. | 25 |
| 31724821 | 2020 | A pathway for assembling [4Fe-4S](2+) clusters in mitochondrial iron-sulfur protein biogenesis. | 25 |
| 27893590 | 2017 | Association study of the GLRX5 rs1007814 polymorphism with schizophrenia in the Han Chinese population. | 0 |
| 27893590 | 2017 | Association study of the GLRX5 rs1007814 polymorphism with schizophrenia in the Han Chinese population. | 0 |
| 24334290 | 2014 | Variant non ketotic hyperglycinemia is caused by mutations in LIAS, BOLA3 and the novel gene GLRX5. | 84 |
| 24334290 | 2014 | Variant non ketotic hyperglycinemia is caused by mutations in LIAS, BOLA3 and the novel gene GLRX5. | 84 |
| 21029046 | 2011 | The crystal structure of human GLRX5: iron-sulfur cluster co-ordination, tetrameric assembly and monomer activity. | 58 |
| 21029046 | 2011 | The crystal structure of human GLRX5: iron-sulfur cluster co-ordination, tetrameric assembly and monomer activity. | 58 |
| 19731322 | 2010 | Systematic molecular genetic analysis of congenital sideroblastic anemia: evidence for genetic heterogeneity and identification of novel mutations. | 56 |
Citation
Dessen P
GLRX5 (glutaredoxin 5)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/63829/glrx5-(glutaredoxin-5)
