GLYR1 (glyoxylate reductase 1 homolog)

2014-11-01  

Identity

HGNC
GLYR1
LOCATION
16p13.3
LOCUSID
84656
ALIAS
BM045,HIBDL,N-PAC,NP60,hNDF
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84656
MIM: 610660
HGNC: 24434
Ensembl: ENSG00000140632

Variants:

dbSNP: 84656
ClinVar: 84656
TCGA: ENSG00000140632
COSMIC: GLYR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000140632ENST00000321919Q49A26
ENSG00000140632ENST00000436648Q49A26
ENSG00000140632ENST00000587297K7EPU6
ENSG00000140632ENST00000587936K7EK70
ENSG00000140632ENST00000588297K7EQB2
ENSG00000140632ENST00000588732K7ELL0
ENSG00000140632ENST00000589389K7EMM8
ENSG00000140632ENST00000591451Q49A26

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
323707862020Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways.7
323707862020Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways.7
309702442019A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.17
309702442019A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.17

Citation

Dessen P

GLYR1 (glyoxylate reductase 1 homolog)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63845/glyr1-(glyoxylate-reductase-1-homolog)