Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2814
MIM: 173511
HGNC: 4443
Ensembl: ENSG00000178732
Variants:
dbSNP: 2814
ClinVar: 2814
TCGA: ENSG00000178732
COSMIC: GP5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000178732 | ENST00000401815 | P40197 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA26716 | COL3A1 | Gene | Pathway | associated | 20938371 | ||
| PA26717 | COL4A1 | Gene | Pathway | associated | 20938371 | ||
| PA26718 | COL4A2 | Gene | Pathway | associated | 20938371 | ||
| PA33384 | PLCB1 | Gene | Pathway | associated | 20938371 | ||
| PA33393 | PLCG2 | Gene | Pathway | associated | 20938371 | ||
| PA35041 | COL1A1 | Gene | Pathway | associated | 20938371 | ||
| PA35042 | COL1A2 | Gene | Pathway | associated | 20938371 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35880886 | 2022 | GP5 regulates epithelial-mesenchymal transition in breast cancer via the PI3K/AKT signaling pathway. | 2 |
| 35880886 | 2022 | GP5 regulates epithelial-mesenchymal transition in breast cancer via the PI3K/AKT signaling pathway. | 2 |
| 23929303 | 2013 | Bernard-Soulier syndrome: an update. | 24 |
| 23929303 | 2013 | Bernard-Soulier syndrome: an update. | 24 |
| 21529934 | 2011 | Delineating the roles of the GPIIb/IIIa and GP-Ib-IX-V platelet receptors in mediating platelet adhesion to adsorbed fibrinogen and albumin. | 18 |
| 21529934 | 2011 | Delineating the roles of the GPIIb/IIIa and GP-Ib-IX-V platelet receptors in mediating platelet adhesion to adsorbed fibrinogen and albumin. | 18 |
| 19874464 | 2010 | The platelet glycoprotein Ib-IX-V complex anchors lipid rafts to the membrane skeleton: implications for activation-dependent cytoskeletal translocation of signaling molecules. | 8 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 19874464 | 2010 | The platelet glycoprotein Ib-IX-V complex anchors lipid rafts to the membrane skeleton: implications for activation-dependent cytoskeletal translocation of signaling molecules. | 8 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
| 18450753 | 2008 | Redundant mechanism of platelet adhesion to laminin and collagen under flow: involvement of von Willebrand factor and glycoprotein Ib-IX-V. | 18 |
Citation
Dessen P
GP5 (glycoprotein V platelet)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/63917/gp5-(glycoprotein-v-platelet)
