Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51206
MIM: 605546
HGNC: 14388
Ensembl: ENSG00000088053
Variants:
dbSNP: 51206
ClinVar: 51206
TCGA: ENSG00000088053
COSMIC: GP6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000088053 | ENST00000310373 | Q9HCN6 |
| ENSG00000088053 | ENST00000333884 | Q9HCN6 |
| ENSG00000088053 | ENST00000417454 | Q9HCN6 |
| ENSG00000088053 | ENST00000468239 | K7EIW7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA26716 | COL3A1 | Gene | Pathway | associated | 20938371 | ||
| PA26717 | COL4A1 | Gene | Pathway | associated | 20938371 | ||
| PA26718 | COL4A2 | Gene | Pathway | associated | 20938371 | ||
| PA33384 | PLCB1 | Gene | Pathway | associated | 20938371 | ||
| PA33393 | PLCG2 | Gene | Pathway | associated | 20938371 | ||
| PA35041 | COL1A1 | Gene | Pathway | associated | 20938371 | ||
| PA35042 | COL1A2 | Gene | Pathway | associated | 20938371 | ||
| PA443796 | Coronary Artery Disease | Disease | ClinicalAnnotation | associated | PD | 16493486 | |
| PA448497 | aspirin | Chemical | ClinicalAnnotation | associated | PD | 16493486 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36990158 | 2023 | Glycoprotein VI interplay with fibrin(ogen) in thrombosis. | 2 |
| 37068592 | 2023 | Protease-activated receptors and glycoprotein VI cooperatively drive the platelet component in thromboelastography. | 1 |
| 37175486 | 2023 | Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets. | 0 |
| 36990158 | 2023 | Glycoprotein VI interplay with fibrin(ogen) in thrombosis. | 2 |
| 37068592 | 2023 | Protease-activated receptors and glycoprotein VI cooperatively drive the platelet component in thromboelastography. | 1 |
| 37175486 | 2023 | Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets. | 0 |
| 35041713 | 2022 | Platelet surface receptor glycoprotein VI-dimer is overexpressed in stroke: The Glycoprotein VI in Stroke (GYPSIE) study results. | 9 |
| 35512832 | 2022 | Platelet Activation via Glycoprotein VI Initiates Thrombin Generation: A Potential Role for Platelet-Derived Factor IX? | 0 |
| 35561312 | 2022 | GPVI expression is linked to platelet size, age, and reactivity. | 7 |
| 35041713 | 2022 | Platelet surface receptor glycoprotein VI-dimer is overexpressed in stroke: The Glycoprotein VI in Stroke (GYPSIE) study results. | 9 |
| 35512832 | 2022 | Platelet Activation via Glycoprotein VI Initiates Thrombin Generation: A Potential Role for Platelet-Derived Factor IX? | 0 |
| 35561312 | 2022 | GPVI expression is linked to platelet size, age, and reactivity. | 7 |
| 33124026 | 2021 | Differential Role of Glycoprotein VI in Mouse and Human Thrombus Progression and Stability. | 3 |
| 33267658 | 2021 | Nonredundant Roles of Platelet Glycoprotein VI and Integrin αIIbβ3 in Fibrin-Mediated Microthrombus Formation. | 12 |
| 33472402 | 2021 | GPVI (Glycoprotein VI) Interaction With Fibrinogen Is Mediated by Avidity and the Fibrinogen αC-Region. | 11 |
Citation
Dessen P
GP6 (glycoprotein VI platelet)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/63918/gp6-(glycoprotein-vi-platelet)
