Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2815
MIM: 173515
HGNC: 4444
Ensembl: ENSG00000169704
Variants:
dbSNP: 2815
ClinVar: 2815
TCGA: ENSG00000169704
COSMIC: GP9
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000169704 | ENST00000307395 | P14770 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA26716 | COL3A1 | Gene | Pathway | associated | 20938371 | ||
| PA26717 | COL4A1 | Gene | Pathway | associated | 20938371 | ||
| PA26718 | COL4A2 | Gene | Pathway | associated | 20938371 | ||
| PA33384 | PLCB1 | Gene | Pathway | associated | 20938371 | ||
| PA33393 | PLCG2 | Gene | Pathway | associated | 20938371 | ||
| PA35041 | COL1A1 | Gene | Pathway | associated | 20938371 | ||
| PA35042 | COL1A2 | Gene | Pathway | associated | 20938371 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33550613 | 2021 | Oxidation shuts down an auto-inhibitory mechanism of von Willebrand factor. | 1 |
| 33550613 | 2021 | Oxidation shuts down an auto-inhibitory mechanism of von Willebrand factor. | 1 |
| 28561420 | 2017 | Cab4b, the first human platelet antigen carried by glycoprotein IX discovered in a context of severe neonatal thrombocytopenia. | 1 |
| 28603902 | 2017 | Extracellular signal-regulated kinase 5 associates with casein kinase II to regulate GPIb-IX-mediated platelet activation via the PTEN/PI3K/Akt pathway. | 13 |
| 28561420 | 2017 | Cab4b, the first human platelet antigen carried by glycoprotein IX discovered in a context of severe neonatal thrombocytopenia. | 1 |
| 28603902 | 2017 | Extracellular signal-regulated kinase 5 associates with casein kinase II to regulate GPIb-IX-mediated platelet activation via the PTEN/PI3K/Akt pathway. | 13 |
| 26203189 | 2015 | The Transmembrane Domains of β and IX Subunits Mediate the Localization of the Platelet Glycoprotein Ib-IX Complex to the Glycosphingolipid-enriched Membrane Domain. | 3 |
| 26203189 | 2015 | The Transmembrane Domains of β and IX Subunits Mediate the Localization of the Platelet Glycoprotein Ib-IX Complex to the Glycosphingolipid-enriched Membrane Domain. | 3 |
| 23995613 | 2014 | Novel genetic abnormalities in Bernard-Soulier syndrome in India. | 5 |
| 23995613 | 2014 | Novel genetic abnormalities in Bernard-Soulier syndrome in India. | 5 |
| 23929303 | 2013 | Bernard-Soulier syndrome: an update. | 24 |
| 23929303 | 2013 | Bernard-Soulier syndrome: an update. | 24 |
| 23143686 | 2012 | Platelets with a W127X mutation in GPIX express sufficient residual amounts of GPIbα to support adhesion to von Willebrand factor and collagen. | 2 |
| 23143686 | 2012 | Platelets with a W127X mutation in GPIX express sufficient residual amounts of GPIbα to support adhesion to von Willebrand factor and collagen. | 2 |
| 21507943 | 2011 | Platelet glycoprotein Ib beta/IX mediates glycoprotein Ib alpha localization to membrane lipid domain critical for von Willebrand factor interaction at high shear. | 7 |
Citation
Dessen P
GP9 (glycoprotein IX platelet)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/63919/gp9-(glycoprotein-ix-platelet)
