Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11245
MIM: 612183
HGNC: 32370
Ensembl: ENSG00000166073
Variants:
dbSNP: 11245
ClinVar: 11245
TCGA: ENSG00000166073
COSMIC: GPR176
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000166073 | ENST00000299092 | Q14439 |
| ENSG00000166073 | ENST00000543580 | Q14439 |
| ENSG00000166073 | ENST00000561100 | Q14439 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by GPCR | REACTOME | R-HSA-372790 |
| GPCR downstream signaling | REACTOME | R-HSA-388396 |
| G alpha (s) signalling events | REACTOME | R-HSA-418555 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38835234 | 2024 | The oncogenic roles of GPR176 in ovarian cancer: a molecular target for aggressiveness and gene therapy. | 0 |
| 38835234 | 2024 | The oncogenic roles of GPR176 in ovarian cancer: a molecular target for aggressiveness and gene therapy. | 0 |
| 36905238 | 2023 | GPR176 Promotes Cancer Progression by Interacting with G Protein GNAS to Restrain Cell Mitophagy in Colorectal Cancer. | 8 |
| 37291181 | 2023 | High expression of GPR176 predicts poor prognosis of gastric cancer patients and promotes the proliferation, migration, and invasion of gastric cancer cells. | 0 |
| 37584712 | 2023 | The promoting effects of GPR176 expression on proliferation, chemoresistance, lipogenesis and invasion of oesophageal cancer. | 0 |
| 36905238 | 2023 | GPR176 Promotes Cancer Progression by Interacting with G Protein GNAS to Restrain Cell Mitophagy in Colorectal Cancer. | 8 |
| 37291181 | 2023 | High expression of GPR176 predicts poor prognosis of gastric cancer patients and promotes the proliferation, migration, and invasion of gastric cancer cells. | 0 |
| 37584712 | 2023 | The promoting effects of GPR176 expression on proliferation, chemoresistance, lipogenesis and invasion of oesophageal cancer. | 0 |
| 28502923 | 2017 | G-protein-coupled receptor signaling through Gpr176, Gz, and RGS16 tunes time in the center of the circadian clock [Review]. | 8 |
| 28502923 | 2017 | G-protein-coupled receptor signaling through Gpr176, Gz, and RGS16 tunes time in the center of the circadian clock [Review]. | 8 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20677014 | 2010 | An approach based on a genome-wide association study reveals candidate loci for narcolepsy. | 19 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20677014 | 2010 | An approach based on a genome-wide association study reveals candidate loci for narcolepsy. | 19 |
Citation
Dessen P
GPR176 (G protein-coupled receptor 176)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/63979/gpr176-(g-protein-coupled-receptor-176)
