Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54103
MIM: 613552
HGNC: 28042
Ensembl: ENSG00000186088
Variants:
dbSNP: 54103
ClinVar: 54103
TCGA: ENSG00000186088
COSMIC: GSAP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000186088 | ENST00000257626 | A4D1B5 |
| ENSG00000186088 | ENST00000415112 | H7C0Q7 |
| ENSG00000186088 | ENST00000430584 | C9JRG7 |
| ENSG00000186088 | ENST00000441833 | B7ZL33 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34156424 | 2021 | GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease. | 12 |
| 34156424 | 2021 | GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease. | 12 |
| 28743126 | 2017 | Frontal Cortex and Hippocampal γ-Secretase Activating Protein Levels in Prodromal Alzheimer Disease. | 6 |
| 28743126 | 2017 | Frontal Cortex and Hippocampal γ-Secretase Activating Protein Levels in Prodromal Alzheimer Disease. | 6 |
| 26076991 | 2015 | Regulation of gamma-secretase activating protein by the 5Lipoxygenase: in vitro and in vivo evidence. | 8 |
| 26076991 | 2015 | Regulation of gamma-secretase activating protein by the 5Lipoxygenase: in vitro and in vivo evidence. | 8 |
| 25037285 | 2014 | Common GSAP promoter variant contributes to Alzheimer's disease liability. | 13 |
| 25037285 | 2014 | Common GSAP promoter variant contributes to Alzheimer's disease liability. | 13 |
| 23209290 | 2013 | The role of γ-secretase activating protein (GSAP) and imatinib in the regulation of γ-secretase activity and amyloid-β generation. | 20 |
| 23209290 | 2013 | The role of γ-secretase activating protein (GSAP) and imatinib in the regulation of γ-secretase activity and amyloid-β generation. | 20 |
| 21718343 | 2012 | Immunohistochemical characterization of γ-secretase activating protein expression in Alzheimer's disease brains. | 14 |
| 22681044 | 2012 | Purification and characterization of the human γ-secretase activating protein. | 9 |
| 21718343 | 2012 | Immunohistochemical characterization of γ-secretase activating protein expression in Alzheimer's disease brains. | 14 |
| 22681044 | 2012 | Purification and characterization of the human γ-secretase activating protein. | 9 |
| 20811458 | 2010 | Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease. | 115 |
Citation
Dessen P
GSAP (gamma-secretase activating protein)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64070/gsap-(gamma-secretase-activating-protein)
