Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2981
MIM: 601271
HGNC: 4683
Ensembl: ENSG00000044012
Variants:
dbSNP: 2981
ClinVar: 2981
TCGA: ENSG00000044012
COSMIC: GUCA2B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000044012 | ENST00000372581 | Q16661 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism | REACTOME | R-HSA-1430728 |
| Miscellaneous digestion events | REACTOME | R-HSA-8935690 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34990711 | 2022 | High plasma and lingual uroguanylin as potential contributors to changes in food preference after sleeve gastrectomy. | 3 |
| 34990711 | 2022 | High plasma and lingual uroguanylin as potential contributors to changes in food preference after sleeve gastrectomy. | 3 |
| 28847213 | 2018 | Immunohistochemical Staining for Uroguanylin, a Satiety Hormone, is Decreased in Intestinal Tissue Specimens From Female Adolescents With Obesity. | 9 |
| 29112082 | 2018 | Pilot Study Measuring the Novel Satiety Hormone, Pro-Uroguanylin, in Adolescents With and Without Obesity. | 8 |
| 29289697 | 2018 | Guanylin and uroguanylin mRNA expression is increased following Roux-en-Y gastric bypass, but guanylins do not play a significant role in body weight regulation and glycemic control. | 7 |
| 30266914 | 2018 | Circulating Pro-Uroguanylin Levels In Children And Their Relation To Obesity, Sex And Puberty. | 2 |
| 28847213 | 2018 | Immunohistochemical Staining for Uroguanylin, a Satiety Hormone, is Decreased in Intestinal Tissue Specimens From Female Adolescents With Obesity. | 9 |
| 29112082 | 2018 | Pilot Study Measuring the Novel Satiety Hormone, Pro-Uroguanylin, in Adolescents With and Without Obesity. | 8 |
| 29289697 | 2018 | Guanylin and uroguanylin mRNA expression is increased following Roux-en-Y gastric bypass, but guanylins do not play a significant role in body weight regulation and glycemic control. | 7 |
| 30266914 | 2018 | Circulating Pro-Uroguanylin Levels In Children And Their Relation To Obesity, Sex And Puberty. | 2 |
| 27044258 | 2016 | Cellular localization of guanylin and uroguanylin mRNAs in human and rat duodenal and colonic mucosa. | 28 |
| 27108812 | 2016 | Guanylin and uroguanylin stimulate lipolysis in human visceral adipocytes. | 17 |
| 27125248 | 2016 | Expression of guanylate cyclase-C, guanylin, and uroguanylin is downregulated proportionally to the ulcerative colitis disease activity index. | 23 |
| 27620667 | 2016 | Structural impact analysis of missense SNPs present in the uroguanylin gene by long-term molecular dynamics simulations. | 1 |
| 27044258 | 2016 | Cellular localization of guanylin and uroguanylin mRNAs in human and rat duodenal and colonic mucosa. | 28 |
Citation
Dessen P
GUCA2B (guanylate cyclase activator 2B)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64113/guca2b-(guanylate-cyclase-activator-2b)
