GYPC (glycophorin C (Gerbich blood group))

2014-11-01  

Identity

HGNC
LOCATION
2q14.3
LOCUSID
ALIAS
CD236,CD236R,GE,GPC,GPD,GYPD,PAS-2,PAS-2
FUSION GENES

Other Information

Locus ID:

NCBI: 2995
MIM: 110750
HGNC: 4704
Ensembl: ENSG00000136732

Variants:

dbSNP: 2995
ClinVar: 2995
TCGA: ENSG00000136732
COSMIC: GYPC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136732ENST00000259254P04921
ENSG00000136732ENST00000356887P04921
ENSG00000136732ENST00000409836P04921

Expression (GTEx)

0
50
100
150
200
250
300
350

Pathways

PathwaySourceExternal ID
MalariaKEGGko05144
MalariaKEGGhsa05144
HemostasisREACTOMER-HSA-109582
Cell surface interactions at the vascular wallREACTOMER-HSA-202733

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
345627712021Novel variant in glycophorin c gene protects against ribavirin-induced anemia during chronic hepatitis C treatment.2
345627712021Novel variant in glycophorin c gene protects against ribavirin-induced anemia during chronic hepatitis C treatment.2
293445812018Glycophorin-C sialylation regulates Lu/BCAM adhesive capacity during erythrocyte aging.14
293445812018Glycophorin-C sialylation regulates Lu/BCAM adhesive capacity during erythrocyte aging.14
282727392017Genetic background of the rare Yus and Gerbich blood group phenotypes: homologous regions of the GYPC gene contribute to deletion alleles.4
282727392017Genetic background of the rare Yus and Gerbich blood group phenotypes: homologous regions of the GYPC gene contribute to deletion alleles.4
246529862014Glycophorin C (CD236R) mediates vivax malaria parasite rosetting to normocytes.30
250111102014STEVOR is a Plasmodium falciparum erythrocyte binding protein that mediates merozoite invasion and rosetting.85
246529862014Glycophorin C (CD236R) mediates vivax malaria parasite rosetting to normocytes.30
250111102014STEVOR is a Plasmodium falciparum erythrocyte binding protein that mediates merozoite invasion and rosetting.85
243792732013[Human erythrocyte glycophorin C as the receptor for EBA-140 Plasmodium falciparum merozoite ligand].4
243792732013[Human erythrocyte glycophorin C as the receptor for EBA-140 Plasmodium falciparum merozoite ligand].4
203062912010A three-stage genome-wide association study of general cognitive ability: hunting the small effects.40
209320762010The Gerbich blood group system: a review.11
203062912010A three-stage genome-wide association study of general cognitive ability: hunting the small effects.40

Citation

Dessen P

GYPC (glycophorin C (Gerbich blood group))

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64137/gypc-(glycophorin-c-(gerbich-blood-group))