Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2999
MIM: 116831
HGNC: 4710
Ensembl: ENSG00000100450
Variants:
dbSNP: 2999
ClinVar: 2999
TCGA: ENSG00000100450
COSMIC: GZMH
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000100450 | ENST00000216338 | P20718 |
| ENSG00000100450 | ENST00000382548 | P20718 |
| ENSG00000100450 | ENST00000557220 | A0A0C4DGJ9 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36006802 | 2023 | Natural Killer Cells Disrupt Nerve Fibers by Granzyme H in Atheriosclerotic Cerebral Small Vessel Disease. | 2 |
| 36006802 | 2023 | Natural Killer Cells Disrupt Nerve Fibers by Granzyme H in Atheriosclerotic Cerebral Small Vessel Disease. | 2 |
| 33737344 | 2021 | Copy number loss in granzyme genes confers resistance to immune checkpoint inhibitor in nasopharyngeal carcinoma. | 15 |
| 33737344 | 2021 | Copy number loss in granzyme genes confers resistance to immune checkpoint inhibitor in nasopharyngeal carcinoma. | 15 |
| 23269243 | 2013 | Identification of SERPINB1 as a physiological inhibitor of human granzyme H. | 15 |
| 23352961 | 2013 | Granzyme H induces cell death primarily via a Bcl-2-sensitive mitochondrial cell death pathway that does not require direct Bid activation. | 2 |
| 23269243 | 2013 | Identification of SERPINB1 as a physiological inhibitor of human granzyme H. | 15 |
| 23352961 | 2013 | Granzyme H induces cell death primarily via a Bcl-2-sensitive mitochondrial cell death pathway that does not require direct Bid activation. | 2 |
| 22156339 | 2012 | Granzyme H of cytotoxic lymphocytes is required for clearance of the hepatitis B virus through cleavage of the hepatitis B virus X protein. | 15 |
| 22156497 | 2012 | Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif. | 9 |
| 22156339 | 2012 | Granzyme H of cytotoxic lymphocytes is required for clearance of the hepatitis B virus through cleavage of the hepatitis B virus X protein. | 15 |
| 22156497 | 2012 | Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif. | 9 |
| 19039329 | 2009 | Cleavage of La protein by granzyme H induces cytoplasmic translocation and interferes with La-mediated HCV-IRES translational activity. | 22 |
| 19039329 | 2009 | Cleavage of La protein by granzyme H induces cytoplasmic translocation and interferes with La-mediated HCV-IRES translational activity. | 22 |
| 17765974 | 2008 | Granzyme H induces apoptosis of target tumor cells characterized by DNA fragmentation and Bid-dependent mitochondrial damage. | 22 |
Citation
Dessen P
GZMH (granzyme H)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64141/chromosome-explorer/new-content/
