Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3003
MIM: 600784
HGNC: 4711
Ensembl: ENSG00000113088
Variants:
dbSNP: 3003
ClinVar: 3003
TCGA: ENSG00000113088
COSMIC: GZMK
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000113088 | ENST00000231009 | P49863 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38092138 | 2024 | Granzyme K- and amphiregulin-expressing cytotoxic T cells and activated extrafollicular B cells are potential drivers of IgG4-related disease. | 2 |
| 38497867 | 2024 | High expression of angiotensin-converting enzyme 2 receptor (ACE-2), transmembrane protease serine (TMPRSS), and P-selectin in platelets lead to thrombosis formation in COVID-19 patients. | 0 |
| 38092138 | 2024 | Granzyme K- and amphiregulin-expressing cytotoxic T cells and activated extrafollicular B cells are potential drivers of IgG4-related disease. | 2 |
| 38497867 | 2024 | High expression of angiotensin-converting enzyme 2 receptor (ACE-2), transmembrane protease serine (TMPRSS), and P-selectin in platelets lead to thrombosis formation in COVID-19 patients. | 0 |
| 36652225 | 2023 | Granzyme K contributes to endothelial microvascular damage and leakage during skin inflammation. | 3 |
| 37449888 | 2023 | Human Granzyme K Is a Feature of Innate T Cells in Blood, Tissues, and Tumors, Responding to Cytokines Rather than TCR Stimulation. | 3 |
| 36652225 | 2023 | Granzyme K contributes to endothelial microvascular damage and leakage during skin inflammation. | 3 |
| 37449888 | 2023 | Human Granzyme K Is a Feature of Innate T Cells in Blood, Tissues, and Tumors, Responding to Cytokines Rather than TCR Stimulation. | 3 |
| 30395844 | 2019 | Granzyme K Expressed by Classically Activated Macrophages Contributes to Inflammation and Impaired Remodeling. | 21 |
| 31563951 | 2019 | Human CCR5high effector memory cells perform CNS parenchymal immune surveillance via GZMK-mediated transendothelial diapedesis. | 28 |
| 30395844 | 2019 | Granzyme K Expressed by Classically Activated Macrophages Contributes to Inflammation and Impaired Remodeling. | 21 |
| 31563951 | 2019 | Human CCR5high effector memory cells perform CNS parenchymal immune surveillance via GZMK-mediated transendothelial diapedesis. | 28 |
| 26936634 | 2016 | Extracellular granzyme K mediates endothelial activation through the cleavage of protease-activated receptor-1. | 28 |
| 26936634 | 2016 | Extracellular granzyme K mediates endothelial activation through the cleavage of protease-activated receptor-1. | 28 |
| 25921628 | 2015 | Effect of carbamate pesticides on perforin, granzymes A-B-3/K, and granulysin in human natural killer cells. | 2 |
Citation
Dessen P
GZMK (granzyme K)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64142/gzmk-(granzyme-k)
