HBG2 (hemoglobin subunit gamma 2)

2014-11-01  

Identity

HGNC
HBG2
LOCATION
11p15.4
LOCUSID
3048
ALIAS
HBG-T1,TNCY
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3048
MIM: 142250
HGNC: 4832
Ensembl: ENSG00000196565

Variants:

dbSNP: 3048
ClinVar: 3048
TCGA: ENSG00000196565
COSMIC: HBG2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196565ENST00000336906P69892
ENSG00000196565ENST00000336906D9YZU9
ENSG00000196565ENST00000380252E9PBW4
ENSG00000196565ENST00000444587A0A0J9YYA3

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Factors involved in megakaryocyte development and platelet productionREACTOMER-HSA-983231

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383320232024Methemoglobin levels in malaria: a systematic review and meta-analysis of its association with Plasmodium falciparum and Plasmodium vivax infections and disease severity.0
383320232024Methemoglobin levels in malaria: a systematic review and meta-analysis of its association with Plasmodium falciparum and Plasmodium vivax infections and disease severity.0
373181022023Can We Estimate Late-Onset Sepsis by Serial Methemoglobin Levels? An Observational Study in Preterm Neonates.0
373181022023Can We Estimate Late-Onset Sepsis by Serial Methemoglobin Levels? An Observational Study in Preterm Neonates.0
343415632021Activation of γ-globin gene expression by GATA1 and NF-Y in hereditary persistence of fetal hemoglobin.19
345357032021Novel variants in Krueppel like factor 1 that cause persistence of fetal hemoglobin in In(Lu) individuals.4
345690562021TEA domain transcription factor 4 modulates repression of fetal haemoglobin by direct binding to the γ-globin gene promoters.0
343415632021Activation of γ-globin gene expression by GATA1 and NF-Y in hereditary persistence of fetal hemoglobin.19
345357032021Novel variants in Krueppel like factor 1 that cause persistence of fetal hemoglobin in In(Lu) individuals.4
345690562021TEA domain transcription factor 4 modulates repression of fetal haemoglobin by direct binding to the γ-globin gene promoters.0
323193262020Multi-Locus Models to Address Hb F Variability in Portuguese β-Thalassemia Carriers.1
325081522020XmnI Polymorphism in Sickle Cell Disease in North Morocco.2
325770472020Thalassemia Major and Intermedia Patients in East Java do not Show Fetal Hemoglobin Level Difference in Relation to XMNI Polymorphism.0
327721412020Association between BCL11A, HSB1L-MYB, and XmnI γG-158 (C/T) gene polymorphism and hemoglobin F level in Egyptian sickle cell disease patients.6
323193262020Multi-Locus Models to Address Hb F Variability in Portuguese β-Thalassemia Carriers.1

Citation

Dessen P

HBG2 (hemoglobin subunit gamma 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64186/hbg2-(hemoglobin-subunit-gamma-2)