Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3048
MIM: 142250
HGNC: 4832
Ensembl: ENSG00000196565
Variants:
dbSNP: 3048
ClinVar: 3048
TCGA: ENSG00000196565
COSMIC: HBG2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000196565 | ENST00000336906 | P69892 |
| ENSG00000196565 | ENST00000336906 | D9YZU9 |
| ENSG00000196565 | ENST00000380252 | E9PBW4 |
| ENSG00000196565 | ENST00000444587 | A0A0J9YYA3 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Hemostasis | REACTOME | R-HSA-109582 |
| Factors involved in megakaryocyte development and platelet production | REACTOME | R-HSA-983231 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38332023 | 2024 | Methemoglobin levels in malaria: a systematic review and meta-analysis of its association with Plasmodium falciparum and Plasmodium vivax infections and disease severity. | 0 |
| 38332023 | 2024 | Methemoglobin levels in malaria: a systematic review and meta-analysis of its association with Plasmodium falciparum and Plasmodium vivax infections and disease severity. | 0 |
| 37318102 | 2023 | Can We Estimate Late-Onset Sepsis by Serial Methemoglobin Levels? An Observational Study in Preterm Neonates. | 0 |
| 37318102 | 2023 | Can We Estimate Late-Onset Sepsis by Serial Methemoglobin Levels? An Observational Study in Preterm Neonates. | 0 |
| 34341563 | 2021 | Activation of γ-globin gene expression by GATA1 and NF-Y in hereditary persistence of fetal hemoglobin. | 19 |
| 34535703 | 2021 | Novel variants in Krueppel like factor 1 that cause persistence of fetal hemoglobin in In(Lu) individuals. | 4 |
| 34569056 | 2021 | TEA domain transcription factor 4 modulates repression of fetal haemoglobin by direct binding to the γ-globin gene promoters. | 0 |
| 34341563 | 2021 | Activation of γ-globin gene expression by GATA1 and NF-Y in hereditary persistence of fetal hemoglobin. | 19 |
| 34535703 | 2021 | Novel variants in Krueppel like factor 1 that cause persistence of fetal hemoglobin in In(Lu) individuals. | 4 |
| 34569056 | 2021 | TEA domain transcription factor 4 modulates repression of fetal haemoglobin by direct binding to the γ-globin gene promoters. | 0 |
| 32319326 | 2020 | Multi-Locus Models to Address Hb F Variability in Portuguese β-Thalassemia Carriers. | 1 |
| 32508152 | 2020 | XmnI Polymorphism in Sickle Cell Disease in North Morocco. | 2 |
| 32577047 | 2020 | Thalassemia Major and Intermedia Patients in East Java do not Show Fetal Hemoglobin Level Difference in Relation to XMNI Polymorphism. | 0 |
| 32772141 | 2020 | Association between BCL11A, HSB1L-MYB, and XmnI γG-158 (C/T) gene polymorphism and hemoglobin F level in Egyptian sickle cell disease patients. | 6 |
| 32319326 | 2020 | Multi-Locus Models to Address Hb F Variability in Portuguese β-Thalassemia Carriers. | 1 |
Citation
Dessen P
HBG2 (hemoglobin subunit gamma 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64186/hbg2-(hemoglobin-subunit-gamma-2)
