HCN3 (hyperpolarization activated cyclic nucleotide gated potassium channel 3)
2014-11-01 Affiliation
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57657
MIM: 609973
HGNC: 19183
Ensembl: ENSG00000143630
Variants:
dbSNP: 57657
ClinVar: 57657
TCGA: ENSG00000143630
COSMIC: HCN3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000143630 | ENST00000368358 | Q9P1Z3 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Neuronal System | REACTOME | R-HSA-112316 |
| Potassium Channels | REACTOME | R-HSA-1296071 |
| HCN channels | REACTOME | R-HSA-1296061 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38636662 | 2024 | Cryo-EM structure of human HCN3 channel and its regulation by cAMP. | 0 |
| 38636662 | 2024 | Cryo-EM structure of human HCN3 channel and its regulation by cAMP. | 0 |
| 37733590 | 2023 | Hyperpolarization-activated cyclic nucleotide-gated cation channel 3 promotes HCC development in a female-biased manner. | 0 |
| 37733590 | 2023 | Hyperpolarization-activated cyclic nucleotide-gated cation channel 3 promotes HCC development in a female-biased manner. | 0 |
| 25987789 | 2015 | Decreased expression of hyperpolarisation-activated cyclic nucleotide-gated channel 3 in Hirschsprung's disease. | 7 |
| 25987789 | 2015 | Decreased expression of hyperpolarisation-activated cyclic nucleotide-gated channel 3 in Hirschsprung's disease. | 7 |
| 23382386 | 2013 | Up-regulation of hyperpolarization-activated cyclic nucleotide-gated channel 3 (HCN3) by specific interaction with K+ channel tetramerization domain-containing protein 3 (KCTD3). | 15 |
| 23382386 | 2013 | Up-regulation of hyperpolarization-activated cyclic nucleotide-gated channel 3 (HCN3) by specific interaction with K+ channel tetramerization domain-containing protein 3 (KCTD3). | 15 |
| 21615589 | 2011 | Genetic analysis of hyperpolarization-activated cyclic nucleotide-gated cation channels in sudden unexpected death in epilepsy cases. | 19 |
| 21615589 | 2011 | Genetic analysis of hyperpolarization-activated cyclic nucleotide-gated cation channels in sudden unexpected death in epilepsy cases. | 19 |
| 16043489 | 2005 | Functional expression of the human HCN3 channel. | 61 |
| 16043489 | 2005 | Functional expression of the human HCN3 channel. | 61 |
Citation
Dessen P
HCN3 (hyperpolarization activated cyclic nucleotide gated potassium channel 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64210/hcn3-(hyperpolarization-activated-cyclic-nucleotide-gated-potassium-channel-3)
