Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 85441
MIM: 611265
HGNC: 30021
Ensembl: ENSG00000130589
Variants:
dbSNP: 85441
ClinVar: 85441
TCGA: ENSG00000130589
COSMIC: HELZ2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000130589 | ENST00000427522 | Q9BYK8 |
| ENSG00000130589 | ENST00000467148 | Q9BYK8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36639706 | 2023 | The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction. | 9 |
| 37602378 | 2023 | HELZ2: a new, interferon-regulated, human 3'-5' exoribonuclease of the RNB family is expressed from a non-canonical initiation codon. | 1 |
| 36639706 | 2023 | The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction. | 9 |
| 37602378 | 2023 | HELZ2: a new, interferon-regulated, human 3'-5' exoribonuclease of the RNB family is expressed from a non-canonical initiation codon. | 1 |
| 34761308 | 2021 | HELZ2 promotes K63-linked polyubiquitination of c-Myc to induce retinoblastoma tumorigenesis. | 2 |
| 34761308 | 2021 | HELZ2 promotes K63-linked polyubiquitination of c-Myc to induce retinoblastoma tumorigenesis. | 2 |
| 23525231 | 2013 | THRAP3 interacts with HELZ2 and plays a novel role in adipocyte differentiation. | 20 |
| 23525231 | 2013 | THRAP3 interacts with HELZ2 and plays a novel role in adipocyte differentiation. | 20 |
| 22446964 | 2012 | Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles. | 292 |
| 22446964 | 2012 | Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles. | 292 |
Citation
Dessen P
HELZ2 (helicase with zinc finger 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64234/helz2-(helicase-with-zinc-finger-2)
