HENMT1 (HEN methyltransferase 1)

2014-11-01  

Identity

HGNC
HENMT1
LOCATION
1p13.3
LOCUSID
113802
ALIAS
C1orf59,HEN1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 113802
MIM: 612178
HGNC: 26400
Ensembl: ENSG00000162639

Variants:

dbSNP: 113802
ClinVar: 113802
TCGA: ENSG00000162639
COSMIC: HENMT1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162639ENST00000370031A0A0A0MRN1
ENSG00000162639ENST00000370032Q5T8I9
ENSG00000162639ENST00000402983Q5T8I9
ENSG00000162639ENST00000420055X6RGV9
ENSG00000162639ENST00000651461Q5T8I9

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Gene Silencing by RNAREACTOMER-HSA-211000
PIWI-interacting RNA (piRNA) biogenesisREACTOMER-HSA-5601884

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
380658972023Screening of potential key genes in esophageal cancer based on RBP and expression verification of HENMT1.0
380658972023Screening of potential key genes in esophageal cancer based on RBP and expression verification of HENMT1.0
292770122018Photoelectrochemical biosensor for HEN1 RNA methyltransferase detection using peroxidase mimics PtCu NFs and poly(U) polymerase-mediated RNA extension.1
297037502018Identification of substrates of the small RNA methyltransferase Hen1 in mouse spermatogonial stem cells and analysis of its methyl-transfer domain.7
292770122018Photoelectrochemical biosensor for HEN1 RNA methyltransferase detection using peroxidase mimics PtCu NFs and poly(U) polymerase-mediated RNA extension.1
297037502018Identification of substrates of the small RNA methyltransferase Hen1 in mouse spermatogonial stem cells and analysis of its methyl-transfer domain.7
286765342017Expression patterns of HENMT1 and PIWIL1 in human testis: implications for transposon expression.20
286765342017Expression patterns of HENMT1 and PIWIL1 in human testis: implications for transposon expression.20

Citation

Dessen P

HENMT1 (HEN methyltransferase 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64236/henmt1-(hen-methyltransferase-1)