Identity
HGNC
LOCATION
6p21.32
LOCUSID
ALIAS
DC-alpha,DX-ALPHA,HLA-DCA,HLA-DXA,HLADQA2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3118
MIM: 613503
HGNC: 4943
Ensembl: ENSG00000237541
Variants:
dbSNP: 3118
ClinVar: 3118
TCGA: ENSG00000237541
COSMIC: HLA-DQA2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000237541 | ENST00000374940 | P01906 |
| ENSG00000237541 | ENST00000374940 | Q76NI6 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37950809 | 2024 | Proteome-wide Mendelian randomization highlights AIF1 and HLA-DQA2 as targets for primary sclerosing cholangitis. | 1 |
| 37950809 | 2024 | Proteome-wide Mendelian randomization highlights AIF1 and HLA-DQA2 as targets for primary sclerosing cholangitis. | 1 |
| 31605414 | 2020 | Association of GWAS-supported noncoding area loci rs404860, rs3117098, and rs7775228 with asthma in Chinese Zhuang population. | 2 |
| 31605414 | 2020 | Association of GWAS-supported noncoding area loci rs404860, rs3117098, and rs7775228 with asthma in Chinese Zhuang population. | 2 |
| 23257407 | 2013 | HLA variants rs9271366 and rs9275328 are associated with systemic lupus erythematosus susceptibility in Malays and Chinese. | 4 |
| 23257407 | 2013 | HLA variants rs9271366 and rs9275328 are associated with systemic lupus erythematosus susceptibility in Malays and Chinese. | 4 |
| 22407913 | 2012 | HLA-DQA2 and HLA-DQB2 genes are specifically expressed in human Langerhans cells and encode a new HLA class II molecule. | 20 |
| 22407913 | 2012 | HLA-DQA2 and HLA-DQB2 genes are specifically expressed in human Langerhans cells and encode a new HLA class II molecule. | 20 |
| 22096524 | 2011 | Evidence for more than one Parkinson's disease-associated variant within the HLA region. | 36 |
| 22125590 | 2011 | Psoriasis regression analysis of MHC loci identifies shared genetic variants with vitiligo. | 23 |
| 22096524 | 2011 | Evidence for more than one Parkinson's disease-associated variant within the HLA region. | 36 |
| 22125590 | 2011 | Psoriasis regression analysis of MHC loci identifies shared genetic variants with vitiligo. | 23 |
| 20159242 | 2010 | Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions. | 132 |
| 20159242 | 2010 | Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions. | 132 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
Citation
Dessen P
HLA-DQA2 (major histocompatibility complex, class II, DQ alpha 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64331/hla-dqa2-(major-histocompatibility-complex-class-ii-dq-alpha-2)
