Identity
HGNC
LOCATION
6p21.32
LOCUSID
ALIAS
DQB2,HLA-DQB1,HLA-DXB
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3120
MIM: 615161
HGNC: 4945
Ensembl: ENSG00000232629
Variants:
dbSNP: 3120
ClinVar: 3120
TCGA: ENSG00000232629
COSMIC: HLA-DQB2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000232629 | ENST00000411527 | P05538 |
| ENSG00000232629 | ENST00000427449 | H0Y7Y7 |
| ENSG00000232629 | ENST00000435145 | A2ADX3 |
| ENSG00000232629 | ENST00000437316 | Q5SR05 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30600606 | 2019 | Association of human leukocyte antigens-DQB2/DPA1/DPB1 polymorphism and pulmonary tuberculosis in the Chinese Uygur population. | 3 |
| 30600606 | 2019 | Association of human leukocyte antigens-DQB2/DPA1/DPB1 polymorphism and pulmonary tuberculosis in the Chinese Uygur population. | 3 |
| 28613373 | 2017 | Lack of association between human leukocyte antigen polymorphisms rs9277535 and rs7453920 and chronic hepatitis B in a Brazilian population. | 1 |
| 28613373 | 2017 | Lack of association between human leukocyte antigen polymorphisms rs9277535 and rs7453920 and chronic hepatitis B in a Brazilian population. | 1 |
| 27394003 | 2016 | Association of HLA-DP/DQ and STAT4 polymorphisms with ankylosing spondylitis in Southwest China. | 3 |
| 27394003 | 2016 | Association of HLA-DP/DQ and STAT4 polymorphisms with ankylosing spondylitis in Southwest China. | 3 |
| 22407913 | 2012 | HLA-DQA2 and HLA-DQB2 genes are specifically expressed in human Langerhans cells and encode a new HLA class II molecule. | 20 |
| 22407913 | 2012 | HLA-DQA2 and HLA-DQB2 genes are specifically expressed in human Langerhans cells and encode a new HLA class II molecule. | 20 |
| 21257290 | 2011 | Differences in self-peptide binding between T1D-related susceptible and protective DR4 subtypes. | 8 |
| 21257290 | 2011 | Differences in self-peptide binding between T1D-related susceptible and protective DR4 subtypes. | 8 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
| 20587610 | 2010 | Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. | 3 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
| 20587610 | 2010 | Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. | 3 |
| 19180512 | 2009 | HLA-E gene polymorphism associated with susceptibility to Kawasaki disease and formation of coronary artery aneurysms. | 25 |
Citation
Dessen P
HLA-DQB2 (major histocompatibility complex, class II, DQ beta 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64332/hla-dqb2-(major-histocompatibility-complex-class-ii-dq-beta-2)
