Identity
HGNC
LOCATION
3q21.3
LOCUSID
ALIAS
C3orf37,DC12,SRAPD1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56941
MIM: 618288
HGNC: 24446
Ensembl: ENSG00000183624
Variants:
dbSNP: 56941
ClinVar: 56941
TCGA: ENSG00000183624
COSMIC: HMCES
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33788831 | 2021 | Loss of the abasic site sensor HMCES is synthetic lethal with the activity of the APOBEC3A cytosine deaminase in cancer cells. | 15 |
| 33788831 | 2021 | Loss of the abasic site sensor HMCES is synthetic lethal with the activity of the APOBEC3A cytosine deaminase in cancer cells. | 15 |
| 31992357 | 2020 | Characterization of global 5-hydroxymethylcytosine in pediatric posterior fossa ependymoma. | 3 |
| 32307824 | 2020 | HMCES safeguards replication from oxidative stress and ensures error-free repair. | 17 |
| 32492421 | 2020 | HMCES Maintains Replication Fork Progression and Prevents Double-Strand Breaks in Response to APOBEC Deamination and Abasic Site Formation. | 32 |
| 32663791 | 2020 | Structural biology of DNA abasic site protection by SRAP proteins. | 10 |
| 33203436 | 2020 | 5-Hydroxymethylation highlights the heterogeneity in keratinization and cell junctions in head and neck cancers. | 8 |
| 31992357 | 2020 | Characterization of global 5-hydroxymethylcytosine in pediatric posterior fossa ependymoma. | 3 |
| 32307824 | 2020 | HMCES safeguards replication from oxidative stress and ensures error-free repair. | 17 |
| 32492421 | 2020 | HMCES Maintains Replication Fork Progression and Prevents Double-Strand Breaks in Response to APOBEC Deamination and Abasic Site Formation. | 32 |
| 32663791 | 2020 | Structural biology of DNA abasic site protection by SRAP proteins. | 10 |
| 33203436 | 2020 | 5-Hydroxymethylation highlights the heterogeneity in keratinization and cell junctions in head and neck cancers. | 8 |
| 31235913 | 2019 | Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition. | 31 |
| 31235913 | 2019 | Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition. | 31 |
| 25471351 | 2015 | 5-Hydroxymethylcytosine, the "Sixth Base", during brain development and ageing. | 12 |
Citation
Dessen P
HMCES (5-hydroxymethylcytosine binding, ES cell specific)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/64342/gene-explorer/submit-meetings/
